ID H6R8N5_NOCCG Unreviewed; 329 AA.
AC H6R8N5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Conserved Phosphoesterase PA-phosphatase related {ECO:0000313|EMBL:CCF61063.1};
GN OrderedLocusNames=NOCYR_0242 {ECO:0000313|EMBL:CCF61063.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF61063.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF61063.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF61063.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FO082843; CCF61063.1; -; Genomic_DNA.
DR AlphaFoldDB; H6R8N5; -.
DR STRING; 1127134.NOCYR_0242; -.
DR KEGG; ncy:NOCYR_0242; -.
DR eggNOG; COG0671; Bacteria.
DR HOGENOM; CLU_052628_1_0_11; -.
DR OrthoDB; 629685at2; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03386; PAP2_Aur1_like; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR026841; Aur1/Ipt1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR PANTHER; PTHR31310; -; 1.
DR PANTHER; PTHR31310:SF7; PA-PHOSPHATASE RELATED-FAMILY PROTEIN DDB_G0268928; 1.
DR Pfam; PF14378; PAP2_3; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008190};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..295
FT /note="Inositolphosphotransferase Aur1/Ipt1"
FT /evidence="ECO:0000259|Pfam:PF14378"
FT REGION 303..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36857 MW; 5F2C9FCCDD59CA12 CRC64;
MGVPTADAPV TQQQRPARRL FRSGVWAGYL AALAVVSVVF GIPTDRIYQA AWIMVGIAAF
NPYRPWREHL RILIDWVPLI AALVVYDHTR GIADKLGMPV RVEELVSAES WLFGGTIPTV
WLQQHLMTGD ERPWWSILTG IVYTSHFIVP WLVAAIFYVQ SRGRWSKYMR RIVLLSYLGL
LTYILVPAAP PWYASREGVI PEDVGRVSGF GFGMVSFDTS ADWLEAQGNL VAALPSLHAA
FSLMVTVALW PFAPKWFRVI LALYPPAMAF TLIYGGEHYT IDVLLGWAYV GVTILLARAW
ERRRPPPPDE PRTPPAVEPE STTDGVREG
//
