ID H6R9M2_NOCCG Unreviewed; 899 AA.
AC H6R9M2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 02-APR-2025, entry version 56.
DE RecName: Full=Phosphoribosyltransferase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=NOCYR_5454 {ECO:0000313|EMBL:CCF66201.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Nocardiaceae; Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF66201.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF66201.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF66201.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
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DR EMBL; FO082843; CCF66201.1; -; Genomic_DNA.
DR RefSeq; WP_014353645.1; NC_016887.1.
DR AlphaFoldDB; H6R9M2; -.
DR STRING; 1127134.NOCYR_5454; -.
DR KEGG; ncy:NOCYR_5454; -.
DR eggNOG; COG0503; Bacteria.
DR eggNOG; COG1358; Bacteria.
DR HOGENOM; CLU_013211_0_0_11; -.
DR OrthoDB; 1663315at2; -.
DR Proteomes; UP000008190; Chromosome.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR InterPro; IPR028157; PELOTA_dom.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR041688; PRTase_2.
DR InterPro; IPR011215; StiP_N.
DR InterPro; IPR022537; TRSP_dom.
DR Pfam; PF15608; PELOTA_1; 1.
DR Pfam; PF15609; PRTase_2; 1.
DR Pfam; PF11202; StiP; 1.
DR Pfam; PF12500; TRSP; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 51..235
FT /note="Orotate phosphoribosyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF15609"
FT DOMAIN 278..435
FT /note="TRSP"
FT /evidence="ECO:0000259|Pfam:PF12500"
FT DOMAIN 535..789
FT /note="Cysteine protease StiP N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11202"
FT DOMAIN 816..895
FT /note="PELOTA RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF15608"
FT REGION 478..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 95718 MW; 6AC83A55069716C3 CRC64;
MSEESTASRD GEVADTAWAT RHLGIELHHE TSYRHGAEPG VLPAELPIAS LIRPGLRRNP
KRAHLLVSTV LGKHLPTDPR VVLDAGNRLG DLVRGALGER DAVVLGFAET ATGLGHCVAD
RIGATCYLHS TRRPVPLAET LTGFEEGHSH ATSHLLQPAP ADIFVNDLPL VLVDDEISTG
DTAMDAVRAL HAFAPRSHYV LASLVDMRTE TDRARFEAAA RELGARIDTV CLAAGRTILP
DGLIDAVQSL PEPQLNPVAP ERGAFHRCEL PWPAHVPEGG RHGILHSDSE AFEAALGSAT
EVLRGRLTSE FADRPVIVLG HEELMYLPLR LAVALADSGI PTRYQTTTRS PAYVLDEPGY
PLRRGFRFTA PESGQDQPRY LYNAHWAEDF IAELEAWSGD VSEAETVRGE PVLVAVVDEP
ADTEELVAAG GLVDVLTASG ADVLVAVLPG ADPRLLHAGR ADAPAVLTSA AAEAAGGAPE
AASGVPETAS ASSEAASASS EVASPVPEVA SAVPEVASAA RETNGARPLY GPEFGSYAPD
DVAWLLKDLS GVDLEADVTE REQRIQAGIA HYAESLPIEY QPDAQYRELF DQVLADSAQR
LALAVGTVAE LVVAERGTDI VLVSLARAGT PVGVLMRRWL RDGRGAGLPS LDIPHYAVSI
VRDRGIDALA LDYLARHHDP ASIVFVDGWT GKGAITRELS DALDAYHAAG GARFNDDLAV
LADPGQCVRT YGTRDDFLIA SACLNSTVSG LVSRTVLNDD LIGPGEFHGA KFYRELAADD
VSGRLIDTVT AAFDAVRERV PATVAGIRAG DRTPTWAGWA SVEQVRAEYG VSSVNFVKPG
VGETTRVLLR RMPWRVLVRE PDAPEHAHIR LLAAARGVPV EVVGDLAYSC MGLIKDVQQ
//
