ID H6R9Y6_NOCCG Unreviewed; 517 AA.
AC H6R9Y6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Propionyl-CoA carboxylase beta chain (PCCase) (Propanoyl-CoA:carbon dioxide ligase) {ECO:0000313|EMBL:CCF62391.1};
GN Name=pccB {ECO:0000313|EMBL:CCF62391.1};
GN OrderedLocusNames=NOCYR_1602 {ECO:0000313|EMBL:CCF62391.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF62391.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF62391.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF62391.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- SIMILARITY: Belongs to the AccD/PCCB family.
CC {ECO:0000256|ARBA:ARBA00006102}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO082843; CCF62391.1; -; Genomic_DNA.
DR RefSeq; WP_014349858.1; NC_016887.1.
DR AlphaFoldDB; H6R9Y6; -.
DR STRING; 1127134.NOCYR_1602; -.
DR KEGG; ncy:NOCYR_1602; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_018822_6_2_11; -.
DR OrthoDB; 9803706at2; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:CCF62391.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 1..254
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 263..501
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 517 AA; 55858 MW; 953D29760037B945 CRC64;
MTTGTETKLD RLREVLATAA EPAGAAGIAK RAQKGIPSAR ERVQSLLDPG TFTEIGGLVR
NPRDPDAMYG DGVVTGHGRI DGRPVVVIAH DQTVYGGSVG EMFGRKLTHI LRFAYEKACP
VVTINDSGGA RIQDAVASLA WFAHMSRCQE RLSGFVPQVS IMLGKCAAGA VYGPINTDVL
VATGKAHMFV TGPEVIKAVT GEDVTAEELG GAEVQARNGV IHQVCETEQD AFDWARKYLS
YLPSSCVEQP PVVNPGLEPE ITAYDLELES IIPDSDREGY DMHEILLRIF DDGDFHEIRA
AHAPNLITGF ARIDGRPVGV LANQPLVLGG ALDANCSDKA TYFIRLCDAF GLPLIFVVDT
PGILPGAEEE RNGVIIRGGR VPRAIIEATV PIINLVVRKV YGGAYGFMAC KQLGADISFA
WPTARIAVIG AEGAVDIAGR RQLQQVPPEQ RAAVREFMIE QYNATVATPW VAAERGYIDA
VIEPSTTRLE LRHALRLLRD KGATVEFNPR KHSLYPM
//
