ID H7C528_HUMAN Unreviewed; 161 AA.
AC H7C528;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Polyhomeotic homolog 3 {ECO:0000313|Ensembl:ENSP00000418835.1};
DE Flags: Fragment;
GN Name=PHC3 {ECO:0000313|Ensembl:ENSP00000418835.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418835.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000418835.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000418835.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC008040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC023891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR MassIVE; H7C528; -.
DR MaxQB; H7C528; -.
DR PeptideAtlas; H7C528; -.
DR ProteomicsDB; 45878; -.
DR Antibodypedia; 33708; 125 antibodies from 24 providers.
DR Ensembl; ENST00000484068.5; ENSP00000418835.1; ENSG00000173889.16.
DR UCSC; uc062pwd.1; human.
DR HGNC; HGNC:15682; PHC3.
DR VEuPathDB; HostDB:ENSG00000173889; -.
DR GeneTree; ENSGT00940000154964; -.
DR HOGENOM; CLU_140086_0_0_1; -.
DR ChiTaRS; PHC3; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000173889; Expressed in endothelial cell and 192 other cell types or tissues.
DR ExpressionAtlas; H7C528; baseline and differential.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF88; POLYHOMEOTIC-LIKE PROTEIN 3; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:H7C528,
KW ECO:0007829|PeptideAtlas:H7C528};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 97..161
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000418835.1"
SQ SEQUENCE 161 AA; 18379 MW; B24965145D5D4201 CRC64;
XRWNRKPDNQ SLGHRGRRPS GPDGAAREHI LRQLPITYPS AEEDLASHED SVPSAMTTRL
RRQSERERER ELRDVRIRKM PENSDLLPVA QTEPSIWTVD DVWAFIHSLP GCQDIADEFR
AQEIDGQALL LLKEDHLMSA MNIKLGPALK ICARINSLKE S
//
