ID H7C5U0_HUMAN Unreviewed; 131 AA.
AC H7C5U0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 3.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Dynamin 1 {ECO:0000313|Ensembl:ENSP00000420808.3};
DE Flags: Fragment;
GN Name=DNM1 {ECO:0000313|Ensembl:ENSP00000420808.3};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000420808.3, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000420808.3, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000420808.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL590708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR IntAct; H7C5U0; 1.
DR MassIVE; H7C5U0; -.
DR PeptideAtlas; H7C5U0; -.
DR ProteomicsDB; 46134; -.
DR Ensembl; ENST00000482638.6; ENSP00000420808.3; ENSG00000106976.22.
DR UCSC; uc064wcp.1; human.
DR HGNC; HGNC:2972; DNM1.
DR VEuPathDB; HostDB:ENSG00000106976; -.
DR GeneTree; ENSGT00940000155214; -.
DR HOGENOM; CLU_1942903_0_0_1; -.
DR ChiTaRS; DNM1; human.
DR Proteomes; UP000005640; Chromosome 9.
DR Bgee; ENSG00000106976; Expressed in right hemisphere of cerebellum and 175 other cell types or tissues.
DR ExpressionAtlas; H7C5U0; baseline and differential.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR000375; Dynamin_stalk.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF32; DYNAMIN-1; 1.
DR Pfam; PF01031; Dynamin_M; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:H7C5U0,
KW ECO:0007829|ProteomicsDB:H7C5U0};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 2..97
FT /note="Dynamin stalk"
FT /evidence="ECO:0000259|Pfam:PF01031"
FT REGION 112..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000420808.3"
SQ SEQUENCE 131 AA; 14987 MW; 5BC53FDC8C42D228 CRC64;
XELSGGARIN RIFHERFPFE LVKMEFDEKE LRREISYAIK NIHGIRTGLF TPDLAFEATV
KKQVQKLKEP SIKCVDMVVS ELTATIRKCS EKLAEHPGNV QRQPEWKKML KGDRTSQRGG
GCPAMGDTWK T
//
