ID H7C717_ENTFA Unreviewed; 388 AA.
AC H7C717;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Xylose repressor, putative {ECO:0000313|EMBL:AAO80391.1};
GN OrderedLocusNames=EF_0550 {ECO:0000313|EMBL:AAO80391.1};
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO80391.1, ECO:0000313|Proteomes:UP000001415};
RN [1] {ECO:0000313|EMBL:AAO80391.1, ECO:0000313|Proteomes:UP000001415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC {ECO:0000256|ARBA:ARBA00002486}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; AE016830; AAO80391.1; -; Genomic_DNA.
DR RefSeq; NP_814320.1; NC_004668.1.
DR RefSeq; WP_002358549.1; NZ_KE136527.1.
DR AlphaFoldDB; H7C717; -.
DR STRING; 226185.EF_0550; -.
DR EnsemblBacteria; AAO80391; AAO80391; EF_0550.
DR KEGG; efa:EF0550; -.
DR PATRIC; fig|226185.45.peg.2491; -.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_1_9; -.
DR Proteomes; UP000001415; Chromosome.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001415}.
SQ SEQUENCE 388 AA; 43247 MW; 95E7D106F90DAD79 CRC64;
MISSKYTIRE QNEAQILNQI IKHREISRAE LSKITSLNKA SVSSITNKLI NDGFIIEKRI
GEATNRGRKP IMLTFNGSSS ALVIAIDLGY NYIDGALASL DGKEIHRVQL IDTYVNKKNV
QDLIHKVFNQ LTSDCPHTHY GIVGMTIALQ GQVLNNKIIS TSYNDLAEIN LVEMLNQEYN
FPVFLQNEAN LSALGEYTFS SDIENLASIS LHSGIGVGLV KNGKLDVGNK GYAGQLGHTI
LFPNGRKCTC GNHGCLEKYC STQVIYHEIS KEKNLNKINS DVVSILYNNK ESKVVKMIEQ
YAYYLSIGVN NAIMLYAPEL VIFNSPLTKK IPDIINIIQR NLNNQFTKDV LVINSPIEWN
PVISGAISLS IQKFLNIEQL KLGKLNKI
//
