ID   H8G4E2_9PSEU            Unreviewed;       970 AA.
AC   H8G4E2;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:EHY87113.1};
GN   ORFNames=SacazDRAFT_00125 {ECO:0000313|EMBL:EHY87113.1};
OS   Saccharomonospora azurea NA-128.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharomonospora.
OX   NCBI_TaxID=882081 {ECO:0000313|EMBL:EHY87113.1};
RN   [1] {ECO:0000313|EMBL:EHY87113.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA-128 {ECO:0000313|EMBL:EHY87113.1};
RX   PubMed=22768365; DOI=10.4056/sigs.2635833;
RA   Klenk H.P., Held B., Lucas S., Lapidus A., Copeland A., Hammon N.,
RA   Pitluck S., Goodwin L.A., Han C., Tapia R., Brambilla E.M., Potter G.,
RA   Land M., Ivanova N., Rohde M., Goker M., Detter J.C., Kyrpides N.C.,
RA   Woyke T.;
RT   "Genome sequence of the soil bacterium Saccharomonospora azurea type strain
RT   (NA-128(T)).";
RL   Stand. Genomic Sci. 6:220-229(2012).
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
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DR   EMBL; CM001466; EHY87113.1; -; Genomic_DNA.
DR   RefSeq; WP_005437649.1; NZ_CM001466.1.
DR   AlphaFoldDB; H8G4E2; -.
DR   HOGENOM; CLU_004665_2_0_11; -.
DR   OrthoDB; 581105at2; -.
DR   Proteomes; UP000004705; Chromosome.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR   PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF17874; TPR_MalT; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00028; TPR; 5.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01091}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          1..92
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51755"
FT   REPEAT          718..751
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DNA_BIND        1..92
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   970 AA;  106746 MW;  3121C00FA276A145 CRC64;
     MAEIRFHLLG PLGAEIDGRQ VPLGGRKPRL LLAALLLESG TLVSTDSLID VVWPEDPPRS
     AAANLRTYVH SLRRVLTEDR IHRGPAGYRI AVARDELDTT VFADHVATAR RAMAEDRPAD
     ALTQLAAAEP HWRGAPLADM PHHHSWGPVL ARLDELRLEA DELRVRARLA CGEHRDVVPD
     LRELLVRDPF REELWAHLIV ALDRCGRRAE AVEAYDEVER LFREEMGAAP GPRLRDLRAR
     LTAPVPPAPR RPPGSPRRTV CQLPLDVPDL TGREEHVADV IALVRRRQAA GDPTVVVISG
     PPGVGKSSLA VHIAHRLRRD TDDDHLHVGL AGTTAAPRRA SDVLGEVLRS LGASDKTLPS
     DESERAAALR SALSHRSSCV VLDDAASAAQ VRPLLPGTGP SVVLVTSRIR MPELTAARHV
     ELDVLDHDSA LRLLSGIVGT ARVQAEPEHA ARIVDSCGKL PLALWVAGAR LAGRRRLSLS
     YFADRLADER RRLDELRVGD LAVRASLELS YARLPGEAAT AFRALGALGP VSFPGWTVGA
     ILAGDNTDTT GADTAEAVLD VLVDAHLVEL VGEDATGAPR YRMHDLLRCY AAERADDTDR
     RRIRRVVEGY YAAASASVER MPVRYFGVAP TPVPPTYWRP HDLDRLVRDP VAWFDAEHPT
     AAALLEPAAG FAADGAAWRL ATVLTPYYDL RNRWEDWWRA DEHALTAARR TGDRHGEAIV
     LRDLGQVRVY QDRYEEALRL FDRSAELFAR LGHAQGEAVA VASRGTVHRI RGDRARALEC
     SRRALELFSQ VGDLHGEAVA RIAIGTVRMD EGAFDNAETW FTDAYALACA IGDRHRAAHA
     VHRQALLHQR RGQLGLARQR LDEAIAVFDD LDDDHCAGYA QQSLGELCLR SGELAHAQLL
     LANSLAVHRD TGDRRSEAVV SQRLGELHES LGQEQTSRDY FHRALALWRE LSAEPQRSAV
     ERRLRPVDEA
//