ID H8GHZ0_METAL Unreviewed; 592 AA.
AC H8GHZ0;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit {ECO:0000313|EMBL:EIC28974.1};
GN ORFNames=Metal_1163 {ECO:0000313|EMBL:EIC28974.1};
OS Methylomicrobium album BG8.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomicrobium.
OX NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC28974.1, ECO:0000313|Proteomes:UP000005090};
RN [1] {ECO:0000313|EMBL:EIC28974.1, ECO:0000313|Proteomes:UP000005090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG8 {ECO:0000313|EMBL:EIC28974.1,
RC ECO:0000313|Proteomes:UP000005090};
RX PubMed=23580712;
RA Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S., Op den Camp H.J.,
RA Vuilleumier S., Bringel F., Dispirito A.A., Murrell J.C., Bruce D.,
RA Cheng J.F., Copeland A., Goodwin L., Hauser L., Lajus A., Land M.L.,
RA Lapidus A., Lucas S., Medigue C., Pitluck S., Woyke T., Zeytun A.,
RA Stein L.Y.;
RT "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT Methylomicrobium album Strain BG8.";
RL Genome Announc. 1:E0017013-E0017013(2013).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CM001475; EIC28974.1; -; Genomic_DNA.
DR RefSeq; WP_005370481.1; NZ_CM001475.1.
DR AlphaFoldDB; H8GHZ0; -.
DR STRING; 686340.Metal_1163; -.
DR eggNOG; COG1894; Bacteria.
DR HOGENOM; CLU_014881_3_1_6; -.
DR Proteomes; UP000005090; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.10.10.1590; NADH-quinone oxidoreductase subunit E; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR041921; NuoE_N.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00644; COMPLEX1_51K_1; 1.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005090};
KW Ubiquinone {ECO:0000313|EMBL:EIC28974.1}.
FT DOMAIN 470..515
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 592 AA; 64803 MW; 6D6065D501034B01 CRC64;
MRPFIQDLAA KHHFQPTRLL EMLREIQARD HHVSNEAVEL LAEALRIPRT RLIDAIEFYS
FFSSTPKGRY ELRISDSITD KMLGKDALID YLSEKLRVPV GGVRSDGLVS LDNTSCTGMC
DQGPAGLVNG HALTRLDRAR IDRIAGLIER QVPLAEWPSE FFHAEDNIRK PGLLLGQPIA
QGEGLKAAYA RGLNQTLAEI DASGLRGRGG AGFKTAAKWR FCAEEAESER YVVCNADEGE
PGTFKDRVLL NAFADQVFEG MTLCAAIVGA QHGFLYLRGE YLHLYDKLQT ILAHRREAGL
LGRGILGRNF DFDIEIRLGA GAYICGEESA LIESLEGKSG IPRNRPPYPV THGYLDKPTV
VNNVESFFAA AAIAVHGGGW FAAHGTGKSK GTKILSVSGD CARPGIYEYP FGTPVRTILD
DCGAEDVLGA QIGGPSGTFV SNREFDRLLA FEDLATGGSF IVFDNRRNIL DIARNFTHFF
AHESCGFCTP CRVGTSLLRK QLDKIYDGHG SAGDVAVLDE ICRLVKTYSH CGLGQTAANP
VLTTLARYPE TYESRLKKIS YEPGFDLDAE LETARRLANR SDAAAHLSQT GE
//
