ID H8GPJ1_METAL Unreviewed; 759 AA.
AC H8GPJ1;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ABC-type multidrug transport system, ATPase component {ECO:0000313|EMBL:EIC30937.1};
GN ORFNames=Metal_3267 {ECO:0000313|EMBL:EIC30937.1};
OS Methylomicrobium album BG8.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomicrobium.
OX NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC30937.1, ECO:0000313|Proteomes:UP000005090};
RN [1] {ECO:0000313|EMBL:EIC30937.1, ECO:0000313|Proteomes:UP000005090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG8 {ECO:0000313|EMBL:EIC30937.1,
RC ECO:0000313|Proteomes:UP000005090};
RX PubMed=23580712;
RA Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S., Op den Camp H.J.,
RA Vuilleumier S., Bringel F., Dispirito A.A., Murrell J.C., Bruce D.,
RA Cheng J.F., Copeland A., Goodwin L., Hauser L., Lajus A., Land M.L.,
RA Lapidus A., Lucas S., Medigue C., Pitluck S., Woyke T., Zeytun A.,
RA Stein L.Y.;
RT "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT Methylomicrobium album Strain BG8.";
RL Genome Announc. 1:E0017013-E0017013(2013).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM001475; EIC30937.1; -; Genomic_DNA.
DR RefSeq; WP_005373888.1; NZ_CM001475.1.
DR AlphaFoldDB; H8GPJ1; -.
DR STRING; 686340.Metal_3267; -.
DR eggNOG; COG1131; Bacteria.
DR eggNOG; COG1716; Bacteria.
DR HOGENOM; CLU_012042_1_1_6; -.
DR Proteomes; UP000005090; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR48041:SF91; ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A; 1.
DR PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF00498; FHA; 2.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00240; FHA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005090};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 523..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 734..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 119..168
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 205..446
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 759 AA; 82151 MW; 90EB652E535DC488 CRC64;
MSQIVVEFRS SFTRSSATAT FTDGKDYVAG SNPACDLPLQ GQDVKAEHAR LSFTLDGLFV
SPFADARITV NGHSAVGKTK LSDGDWLALG ATLFQVNFLD HPTGTSPFAA PASPKSGVLT
IGRIPECDLE IASPLVSREH ARLYCDANGV EIEDLNSTNG TFVNGRQIEG RLRLKQGDRV
SIASFGFLFT GQALEPIDTS GRVRVEVQGL CKEVFDRSTK QSKRLLDDIS LAIEPGEFVV
LFGTSGSGKS TLLDALNGRR PATSGKVLYN GIDLYGAFDA FRATIGYVPQ QDIVHRKITI
QNALKYTARL RLPPDTSDRE IGGYIGSVLS KVELSEKSAL PIDTPAPLSG GQLKRVSLAV
ELVANPNILF LDEVTSGLDA GTDKRMMRLF ADLAADEKTV VCVTHTLENI DVCHLVVLLH
KGKLVYFGPP REAAAYFGVQ KLSDVYELLE ASPANLWADK FRQSSYYQNY VLARMTSPAS
ALNSATQPIP PNEAKNRRWF DWRQTGTLIR RYLDLIASDK KNLLILLLQA PLIAVIIGLV
FNTDGLPAQR AEAESKIFFI LVLSAIWFGT LNSARELVKE LPIYLRERSV NLGITPYLTS
KLLPLAALCL IQCALLFGIV SLMVDLPGGF FARVAVLFSA AMAATCMGLA VSAFVDSNDK
AVATAPILLI PQVVLSNAVV ILSDGGLWVA KTSVIAYWAL DAMKTTLSLQ SRSVQYPFTG
KLIVPISGTF GADLGMVALL GIVFIGIAVL GLKLKDRRK
//
