ID H8KNI0_SOLCM Unreviewed; 939 AA.
AC H8KNI0;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN OrderedLocusNames=Solca_2959 {ECO:0000313|EMBL:AFD07978.1};
OS Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB
OS 12057 / USAM 9D) (Flexibacter canadensis).
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Solitalea.
OX NCBI_TaxID=929556 {ECO:0000313|EMBL:AFD07978.1, ECO:0000313|Proteomes:UP000007590};
RN [1] {ECO:0000313|Proteomes:UP000007590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D
RC {ECO:0000313|Proteomes:UP000007590};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Lu M.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Schroeder M., Kopitz M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Solitalea canadensis DSM 3403.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; CP003349; AFD07978.1; -; Genomic_DNA.
DR RefSeq; WP_014681205.1; NC_017770.1.
DR AlphaFoldDB; H8KNI0; -.
DR STRING; 929556.Solca_2959; -.
DR KEGG; scn:Solca_2959; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_0_2_10; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000007590; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007590};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 257..591
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 603..935
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 939 AA; 104899 MW; F0B1BB53DDADF5A6 CRC64;
MNKNIDEVSA KSHIVIKGAR VHNLKNIDVA IPKNKLVVIT GLSGSGKSSL AFDTLYAEGQ
RRYVESLSAY ARQFMGRMNK PDVDYIKGIA PAIAIEQKVN ATNPRSTVGT STEIYDYLKL
LFARIGRTIS PVSGREVRKD TVTSVTDFVL SIPDDTAVNI YCPLQPHNNR SLKEELAVLL
QKGFKRVAYH SNVSKIEDIL DDKSIDANHP LREGELRILV DRIIIDREDD TLNRISDSVQ
TAFFEGKGDA YVQYANEEGE SVETHFCDRF ELDELRFEEP TPQFFSFNNP FGACKTCEGY
GNVIGIDPDL VIPDKSKSIY ETAIAPWRGE KMKEWNETLI KHAAKFDFPI HRPYIELTEE
QKELLWTGNK YFGGLDDFFK DLETQTYKIQ YRVILSRYRG KTVCPDCKGS RLRKDASYVK
IAHKSITDIV LMPLEKASKF FNEIQLNEHD TQIAKRLLIE IQNRLRFLND VGLGYLTLNR
LSNTLSGGES QRINLATSLG SSLVGSVYVL DEPSIGLHPR DTNRLVGVLK SLRNAGNSVL
VVEHEEEIMH AADHLIDIGP RAGVNGGELI FEGNFEEIIK DKASLTGQYL SGKKEIATPK
QRRKWSDFIK VEGARENNLK NIDVKFPLHT MTCVTGVSGS GKTSLVKRIL YPALQKAIGN
FTGEQSGAFN NISGDISKVA QIEMIDQNPI GRSSRSNPVT YVKAYDEIRN LFAAQSAAKA
SGLKPSAFSF NVEGGRCDTC QGEGEVKIEM QFMADIYLPC ETCGGKRFKQ HVLDVKYKEK
DIAEVLDLSI DEALEFFADD KKILTKIQPL QDVGLGYVKL GQSSNTLSGG EAQRIKLASF
LVKGHNPHHT LFIFDEPTTG LHFDDINKLM KSFDALIAQG NTIIVIEHNM DVIKCADWII
DIGPEGGDKG GALVFEGLPE DLVKCENSYT GKFLKERFK
//
