ID H8MZH3_CORCM Unreviewed; 1035 AA.
AC H8MZH3;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=RND multidrug efflux transporter {ECO:0000313|EMBL:AFE07960.1};
GN Name=acrB {ECO:0000313|EMBL:AFE07960.1};
GN OrderedLocusNames=COCOR_06809 {ECO:0000313|EMBL:AFE07960.1};
OS Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)
OS (Myxococcus coralloides).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Corallococcus.
OX NCBI_TaxID=1144275 {ECO:0000313|EMBL:AFE07960.1, ECO:0000313|Proteomes:UP000007587};
RN [1] {ECO:0000313|EMBL:AFE07960.1, ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RX PubMed=22582372; DOI=10.1128/JB.00397-12;
RA Huntley S., Zhang Y., Treuner-Lange A., Kneip S., Sensen C.W.,
RA Sogaard-Andersen L.;
RT "Complete Genome Sequence of the Fruiting Myxobacterium Corallococcus
RT coralloides DSM 2259.";
RL J. Bacteriol. 194:3012-3013(2012).
RN [2] {ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RA Huntley S., Zhang Y., Treuner-Lange A., Sensen C.W., Sogaard-Andersen L.;
RT "Genome sequence of the fruiting myxobacterium Corallococcus coralloides
RT DSM 2259.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003389; AFE07960.1; -; Genomic_DNA.
DR RefSeq; WP_014399595.1; NC_017030.1.
DR AlphaFoldDB; H8MZH3; -.
DR STRING; 1144275.COCOR_06809; -.
DR KEGG; ccx:COCOR_06809; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_7; -.
DR InParanoid; H8MZH3; -.
DR OrthoDB; 9807612at2; -.
DR Proteomes; UP000007587; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF14; BLL4319 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007587};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 844..863
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 870..890
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 910..935
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 956..975
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 987..1013
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1035 AA; 111604 MW; 5237E2D1E81F4961 CRC64;
MKFTDLFIRR PVVALVVNLI IIIAGLQALR SLNVRQYPRS ENADITVTTV YVGANAELVR
GFITTPLERV IAAADGIDYV ESTSSQNISI IRARLKLNYD ANRALSEISA KVDQVRGDLP
PESQVPVMGI ESADSQFAVA YLNFTSDFLE QNELSDYLVR VVQPRLSSVE GVQRADILGA
RTFAMRVWMK PDQMAALNVS PIQVRQALAT NNSLAAVGQT KGSLVQVNLT ANTGLRSVEE
FKQLIVRKDG GAVVRLSDVA DVVLGAEDYD TDVTLNGKTA VFVGIWSLPN ANSLDVMQRI
RQEMDSLKKD LPEQIHGGVA FDGTDYIQNA IDEVVSTLIE TLIIVVIVIF LFLGSVRSIL
VPVVAIPVSL IGTVFLMQVF GFTVNLLTLL AVVLSVGLVV DDAIVVVENV ERHLRAGLRP
VDAAIKSARE LVGPIIAMTL TLAAVYAPIA FQGGLTGSLF REFALTLAGA VTLSGVVALT
LSPMMSSVLL KAGHEDMGLA GVINRGFERL RAAYARTLDS SLLVRGPIYA AWIFLSLLAL
VMFNQSAREL APVEDQDFVI GIMSTPSNST LDQLKPSVTK TSELLMDMPE SSFNFQIVQP
SNGFWGLVLK PFKERQRTTA QVMAEAQERV NTIPAVQTFT LQPPALPGGG NFPVEFVIAS
TAEADELLGF AQQLQEKATQ SGLFAFPPII DVKLDQPQSE LEVDREKVAQ LGLNLGTVGQ
DLGSAVGGNF VNRFNIAGRS YKVIPQVLRS SRLTPEQLKD IHVTGPDGKL VALSAIASLK
DKVAPRSLNR FQQLNAVKLS GVAIRPLDEA LTYLETEAAR ILPAGYRIDY TGESRQLRTE
GDSFAPAFGL AVVLIFLVLA AQFNSFRDPL IILAGSVPLA LFGALVTTFL RMPNPMMPYF
TDSFTTTLNI YSQVGLVTLV GLIAKNGILI VDFANRLQEE GKSKLEAVKE AASERLRPIL
MTTVATVAGH FPLVLVSGPG AAARNSIGLV LVTGMALGTL FTLYFVPAIY LLIAKTRTVA
TSDAAELQQA PDAAA
//
