ID H8WHD1_CAEBR Unreviewed; 383 AA.
AC H8WHD1;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN Name=pro-3 {ECO:0000313|WormBase:CBG23585};
GN Synonyms=Cbr-pro-3 {ECO:0000313|EMBL:CCG58592.1};
GN ORFNames=CBG23585 {ECO:0000313|WormBase:CBG23585}, CBG_23585
GN {ECO:0000313|EMBL:CCG58592.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CCG58592.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CCG58592.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CCG58592.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family.
CC {ECO:0000256|RuleBase:RU365057}.
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DR EMBL; HE601537; CCG58592.1; -; Genomic_DNA.
DR RefSeq; XP_002647810.1; XM_002647764.1.
DR AlphaFoldDB; H8WHD1; -.
DR STRING; 6238.H8WHD1; -.
DR EnsemblMetazoa; CBG23585.1; CBG23585.1; WBGene00041908.
DR GeneID; 8589808; -.
DR KEGG; cbr:CBG_23585; -.
DR CTD; 8589808; -.
DR WormBase; CBG23585; CBP24503; WBGene00041908; Cbr-pro-3.
DR eggNOG; KOG2229; Eukaryota.
DR OMA; DIRTANM; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 93..383
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 44086 MW; 682A76A276B2310E CRC64;
MGKSSKIEKK SKKDGKNGGP KAPEGANSGK ASRFTMSERN LGLMQEIIRK DPESYKEEFL
EQFNYFVQTM KLLHLQPEQN RQETQSLQDS VLFLSGLAKH YPKEAKQFAD SLFELLRVQG
AGLDADVRMS FCKALVLLRN QDMLDPIVLL ETFFELVKVE DKVLRKFLLA SISAHLKRVY
HKKKDVKMLG RIQNLCFSKI KDSRSIVARA AQLVCIDAFR RKFWRDARTA NVIADACFHK
VPKIQVTSLK FFLGSENDNG EEGDDDDSAI DSDAEDNKKT LKEVMTSFRN VKKTRKREKN
VERAKKMISK KKKQKKEGRS KECNLMAIQS LYDPQEFTDK LFGALESKKM DKFEVKVLKI
ALCARIIGIH RLHTLSFYSY LHR
//
