ID H8XUX7_FLAIG Unreviewed; 342 AA.
AC H8XUX7;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN Name=menF {ECO:0000313|EMBL:CCG53905.1};
GN OrderedLocusNames=KQS_09880 {ECO:0000313|EMBL:CCG53905.1};
OS Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1094466 {ECO:0000313|EMBL:CCG53905.1, ECO:0000313|Proteomes:UP000007599};
RN [1] {ECO:0000313|EMBL:CCG53905.1, ECO:0000313|Proteomes:UP000007599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17447 / CIP 109464 / GPTSA100-9
RC {ECO:0000313|Proteomes:UP000007599};
RX PubMed=22582381; DOI=10.1128/JB.00420-12;
RA Barbier P., Houel A., Loux V., Poulain J., Bernardet J.F., Touchon M.,
RA Duchaud E.;
RT "Complete Genome Sequence of Flavobacterium indicum GPSTA100-9T, Isolated
RT from Warm Spring Water.";
RL J. Bacteriol. 194:3024-3025(2012).
RN [2] {ECO:0000313|Proteomes:UP000007599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17447 / CIP 109464 / GPTSA100-9
RC {ECO:0000313|Proteomes:UP000007599};
RA Barbier P., Houel A., Loux V., Poulain J., Bernardet J.-F., Touchon M.,
RA Duchaud E.;
RT "Complete genome sequence of Flavobacterium indicum GPTSA100-9T, isolated
RT from warm spring water.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; HE774682; CCG53905.1; -; Genomic_DNA.
DR RefSeq; WP_014389023.1; NC_017025.1.
DR AlphaFoldDB; H8XUX7; -.
DR STRING; 1094466.KQS_09880; -.
DR KEGG; fin:KQS_09880; -.
DR PATRIC; fig|1094466.5.peg.1939; -.
DR eggNOG; COG1169; Bacteria.
DR HOGENOM; CLU_006493_8_0_10; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000007599; Chromosome.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CCG53905.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007599}.
FT DOMAIN 91..331
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 342 AA; 39096 MW; 431F4842DAEF6B8F CRC64;
MLLLEKASHY FSKKLPFALF VKPNQVQLNG VFQNTDELVE FSGQKGFVFS GFYNTKDVVL
PFDSCEVIQE NWSYEKHYQE RIYFSDSEGV EFKNLVQKGI NAIVENQFEK VVLSRKIEIP
NDTINSIESF KNLVNTYSTA FRYLFYHPQI GLWMGATPEQ LVKIKNGEFY TMALAGTQPY
SEHIVWGEKE IKEQELVTDF IKNQIEDKVD TIKISDAITH RAGSIVHLKT DISGSIKSSI
QPLVLVKALH PTSAVCGMPL QQARSFILEH EGYDRKYYSG YLGEWKGMEN SDLFVNLRCC
EFLENAVAVY VGCGITKDSI PEHEFIETFN KSRTIVSILV RG
//
