ID H8YWV2_9GAMM Unreviewed; 529 AA.
AC H8YWV2;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=Thi970DRAFT_00568 {ECO:0000313|EMBL:EIC22928.1};
OS Thiorhodovibrio frisius.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiorhodovibrio.
OX NCBI_TaxID=631362 {ECO:0000313|EMBL:EIC22928.1, ECO:0000313|Proteomes:UP000002964};
RN [1] {ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Overmann J.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EIC22928.1, ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|EMBL:EIC22928.1,
RC ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Zhang X., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Vogl K., Liu Z.,
RA Overmann J., Frigaard N.-U., Bryant D., Woyke T.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; JH603168; EIC22928.1; -; Genomic_DNA.
DR AlphaFoldDB; H8YWV2; -.
DR STRING; 631362.Thi970DRAFT_00568; -.
DR eggNOG; COG1169; Bacteria.
DR HOGENOM; CLU_006493_8_4_6; -.
DR Proteomes; UP000002964; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000002964}.
FT DOMAIN 266..518
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 529 AA; 57979 MW; 783626D4056461FE CRC64;
MSAGYNGGDI LPFTQSLLPA DGYSCVESFQ LNTDNARPAP SHLASTTEGV HADWTPSARD
VIKTLRDRLA AEMARLPLGR HEATANALTS LILPLPQRPT AIAQLPGAQF QFLHPQGESL
RAGYGQALHW EAQGPQRLSE LARITHDWPH CWEQLDPGAT GLKAFAMLGF AAAPNPVTHP
ITPPVPPENA NDDLPNALLW VPDIALRQTA EQAALIFTAP QRQTRTFVQA RWHALLEALI
PRLFPPPRRP ALVTRVLGDS AEPEATEWTR LVELALARIQ AGDLQKVVLS RRLKVSGSRS
FDIARLLDVL AAVFPSCQII NLRHHGSSFV AATPERLLHL RNGRLAVDAI AGTTEHCDCE
DRNLALGQEL LRSEKNLREH GFVVDAVARA LTPFCRSIHV PTQPELMRLR NAQHLWSPIT
AEIDPGTDFF DLADRLHPTP ATNGQPRLAA HHWLREHEPF SRGWYTGAAG FIEPGTGGEL
WVLLRCARIR GKAAELHAGA GIVAGSDPQA EWEETEAKLA AMLTALRFA
//
