ID H8Z1L3_9GAMM Unreviewed; 489 AA.
AC H8Z1L3;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Radical SAM additional 4Fe4S-binding domain protein {ECO:0000313|EMBL:EIC21458.1};
GN ORFNames=Thi970DRAFT_01668 {ECO:0000313|EMBL:EIC21458.1};
OS Thiorhodovibrio frisius.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiorhodovibrio.
OX NCBI_TaxID=631362 {ECO:0000313|EMBL:EIC21458.1, ECO:0000313|Proteomes:UP000002964};
RN [1] {ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Overmann J.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EIC21458.1, ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|EMBL:EIC21458.1,
RC ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Zhang X., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Vogl K., Liu Z.,
RA Overmann J., Frigaard N.-U., Bryant D., Woyke T.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; JH603169; EIC21458.1; -; Genomic_DNA.
DR AlphaFoldDB; H8Z1L3; -.
DR STRING; 631362.Thi970DRAFT_01668; -.
DR eggNOG; COG0535; Bacteria.
DR HOGENOM; CLU_009273_4_2_6; -.
DR OrthoDB; 9792276at2; -.
DR Proteomes; UP000002964; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002964};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 7..215
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
FT REPEAT 392..425
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 489 AA; 54113 MW; 5F5B7B6170248D46 CRC64;
MNASSTQGYP RTAVWELTLA CNMRCQHCGS SCTNKSPDEL DTEAALDLCD QLADLGVELV
TLSGGEPLLR DDWDRIGSRL SEKGVRVNMI SNGWLLDSDT ASRACEAGFG NCAVSLDGTK
EVHDTLRRDG SFERACNALE TLRQAGLGSA VITTVMQDNL ALLPKMRPLL EDLGIQHWQL
QLGMPMGKMT MDRVIAPEQV EEIVSFGRAL LDSSPIQPVL ADCVGYYSHH HQEIRKSYFD
SDHPWQGCNA GKSNIGILHN GDILGCTSIR APEFVEGNIR RTPLSVIWNR PGAFAWNRDF
SVEDLGGFCA KCRYGEICLG GCQNVKLTMT QSLRDNPYCA YRTQVEELSP KIHRMRNVDQ
LLDRARKALA MELFEVAETC LLQANTLSSD NLDILQLLGY AHFRCRQYEK SRDINEQALM
IAPNDAYSWH GLGNALAKLG NIPEAKQAML RARDQAGDAG PLLSEIENDL SILMGGEIQT
TNMQNTSIR
//
