ID H8Z540_9GAMM Unreviewed; 1490 AA.
AC H8Z540;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Thi970DRAFT_04083 {ECO:0000313|EMBL:EIC20447.1};
OS Thiorhodovibrio frisius.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiorhodovibrio.
OX NCBI_TaxID=631362 {ECO:0000313|EMBL:EIC20447.1, ECO:0000313|Proteomes:UP000002964};
RN [1] {ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Overmann J.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EIC20447.1, ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|EMBL:EIC20447.1,
RC ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Zhang X., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Vogl K., Liu Z.,
RA Overmann J., Frigaard N.-U., Bryant D., Woyke T.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; JH603170; EIC20447.1; -; Genomic_DNA.
DR STRING; 631362.Thi970DRAFT_04083; -.
DR eggNOG; COG0642; Bacteria.
DR HOGENOM; CLU_249188_0_0_6; -.
DR OrthoDB; 9180959at2; -.
DR Proteomes; UP000002964; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01007; PBP2_BvgS_HisK_like; 2.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 6.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00497; SBP_bac_3; 3.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00062; PBPb; 3.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 3.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EIC20447.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000002964};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000313|EMBL:EIC20447.1}.
FT DOMAIN 1021..1246
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1272..1391
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 67..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1324
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1490 AA; 162328 MW; 3FEFD9EE049BB890 CRC64;
MSGGKSRASV HIRVLPGLLW LALLWVVMAA PVTAMGAAVG ADQETASDAP EKARALLQAD
ANADANADAN VGSNANSNAR SRARSDSGSG AASRAEPSVA LSPEQRAWLD AHPQIILGSS
DQFPPAVMRA PDGRLIGLMM DILHLLNQRL GSNIQVRGEP AWAGITEQAL TGELDGLLTV
ARLPFWREHF LLTDTIVKTQ VYIFARDGER LASNRISALF GRRVGVFRGL KHINGLVGAH
PDEIEVVRYD SNEDMAAALI AGEVDFLVAD GTFDWWRREN TLVGFGMVGI LDGGDYEVAA
AVRKDWPELV EMLNLGLASI GAAEHAAIRE RWMGVLDQPA PGDFALPVLA DLELTAAERA
WLDAHPEILL GISDQFLPDI IIGPNGRQSG LVVDFLRLLN VPLSGRLKLH VERDWRAVTD
QAIAHEIDGL ASSAPNPAWD AHFLYTDPLY HGFFSFYRCA DDPPITRVEQ LDGLRVGYLA
GMKKVEQLLG EVPDAALVPL ASNRAMATAL ISGEVDVLIG AIDLEWWRRQ NSALAFGPTG
TLAGSEHPVL MSIRDDWPEL VGILNKALRA IPDDQRARIY QRWLGETRAL RGPALALSSE
ARAWLRAHPT IRFAVSRDWA PIGFYDRDDQ PAGIAPDYLA RIGELLGVRF EPVAVADWPQ
AMDGLARGRL DLLPAMAPTA EREKRFVFTV PYLDFPVAIF ARVETPLINR LDALNGQRVI
IIDGHATQEW LQRDYPDIRL LRVRDAYGAV RALAEGQGDA LVGNLFAISQ AVAHEKLFQI
RVAGGTPYSY RLAMATRPDW APLIDILDTA MAAIPAAERD AIQSRWMREV PSSPMDYGLI
WRLAAAAALV LGLVLLWNLS LRRQVQRRRL AEQVLGRSET LLRNTLDATE NGVLVSGADG
RLLSVNRRFQ QLWDIPDDWL VPSGGDDTLL SRVKQQLVDP EGFLTRVREL YASDDEAVDT
LVFRDGRVFS RYSRPLEIGG QRARLWSFTD ITERERVMAD LHQAKQAAEA ASRAKSDFLA
NMSHEIRTPM NAILGMLHLA LQSDLDLRLR GYLDKAQTAA HNLLGLLNDI LDLSKVEANQ
LRLEQVPFAL SELLENLSAV VGQQARDKGL DFRVARGHDL PDQFVGDSLR LSQILTNLAG
NGVKFTEGGE VRVEVRQTAD ISGKGAGRVA LEFIVSDTGI GMDSAMVARL FEPFQQADTS
TTRRYGGTGL GLSICKRLVD LMGGDIQVES EVGVGTRFSI RLSFARAKVQ AAAKAGAGGL
AAENSASLVG RRVLVVEDNE VNREVARALL EREGLNVSIA EDGLQAVERL ERDGCDAFDL
VLMDVQMPNL DGYGATARVR ALPGGDALPI IGVTAHARPE DIARVLGAGM NAYISKPIDV
WRLMATIAEQ LGGRSAAQVN AAASTSAEIR ADNGEPLDLA ALLETLAAKA ARNDVSIEDD
FRAARSVLSQ RLPPADYRAL ADAIASCRFE AVDQLISRWQ GIDASAAARR
//
