ID H8Z7K4_9GAMM Unreviewed; 368 AA.
AC H8Z7K4;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:EIC20934.1};
GN ORFNames=Thi970DRAFT_04609 {ECO:0000313|EMBL:EIC20934.1};
OS Thiorhodovibrio frisius.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiorhodovibrio.
OX NCBI_TaxID=631362 {ECO:0000313|EMBL:EIC20934.1, ECO:0000313|Proteomes:UP000002964};
RN [1] {ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Overmann J.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EIC20934.1, ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|EMBL:EIC20934.1,
RC ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Zhang X., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Vogl K., Liu Z.,
RA Overmann J., Frigaard N.-U., Bryant D., Woyke T.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; JH603170; EIC20934.1; -; Genomic_DNA.
DR RefSeq; WP_009151337.1; NZ_JH603170.1.
DR AlphaFoldDB; H8Z7K4; -.
DR STRING; 631362.Thi970DRAFT_04609; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_0_1_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000002964; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF29; BLR2860 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002964}.
FT DOMAIN 88..280
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 147..174
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 368 AA; 39848 MW; F0FE1CA0A73B30C9 CRC64;
MNRRTLRPFQ RRSGVSLGLA LALALAVTLW MLSGSFVGSG EGEQEPEDPA RSAARLRVQV
TDSLAQRVTN EVVVQGQLEP WRRLTLRAQV EGKVTALPVE KGAWVEADTL LVELAEDDRP
AQLARAQADV AARELELSAA ETLGQRGMQA QTQIKTAQAE LARAQAEATR LRLEMEWLAI
RAPFAGVIDG RDVELGSFLQ RADAIVELVD DSRLKATAQV PQQRAGALAI GQPVAVELLD
GTLAQGRLIY ISRVADAKTR GFRIEAEVPN AERRLASGVS AELRIHTGEV DGHFLSPAAL
TLNDKGEIGV RTLDAENRVQ FVRVDLLRTQ SDGLWVSGLP ASARIITRGQ GFVSEGEQVE
PVPQEDGV
//
