ID   H9G593_ANOCA            Unreviewed;       341 AA.
AC   H9G593;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 3.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=BAR domain-containing protein {ECO:0000259|PROSITE:PS51021};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000001464.4, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000001464.4}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000001464.4};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000001464.4}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell projection, podosome
CC       {ECO:0000256|ARBA:ARBA00004188}. Cytoplasm
CC       {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the endophilin family.
CC       {ECO:0000256|ARBA:ARBA00006697}.
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DR   AlphaFoldDB; H9G593; -.
DR   STRING; 28377.ENSACAP00000001464; -.
DR   Ensembl; ENSACAT00000001500.4; ENSACAP00000001464.4; ENSACAG00000001404.4.
DR   eggNOG; KOG1118; Eukaryota.
DR   GeneTree; ENSGT00940000154737; -.
DR   HOGENOM; CLU_047887_0_0_1; -.
DR   InParanoid; H9G593; -.
DR   TreeFam; TF313281; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000001404; Expressed in hemipenis and 12 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0098978; C:glutamatergic synapse; IBA:GO_Central.
DR   GO; GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0098793; C:presynapse; IBA:GO_Central.
DR   GO; GO:0016191; P:synaptic vesicle uncoating; IBA:GO_Central.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   PANTHER; PTHR14167:SF63; ENDOPHILIN-A2; 1.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   Pfam; PF03114; BAR; 1.
DR   SMART; SM00721; BAR; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51021; BAR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT   DOMAIN          49..280
FT                   /note="BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51021"
FT   REGION          275..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..296
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..330
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   341 AA;  38666 MW;  520170EF2CBC5371 CRC64;
     MSYIASNGLR LCCQLGLDLI ISRERLIQLI KKAENFGLSL SMYGNCSSRQ SLEVSHSLYF
     SEALFLFLQK VDLTSKAVVE VLARTTEYLQ PNPASRAKLT MLNTVSKIRG QVKNPGYPQS
     EGLLGESMIR YGKELGEESN FGDALLDAGE SMKRLAEVKD SLDIEVKQNF IDPLQNLCDK
     DLKEIQHHLK KLEGRRLDFD YKKKRQGKIP DEELRQALEK FEESKEVAET SMHNLLETDI
     EQVSQLSALV DAQLDYHRQA VQILDELADK LKRRVREASS RPKREYKPKP RETYEFGESD
     QSNGGFSCNP APKVSAASSS FRSEKPSRTP SRTFCECLCL L
//