ID H9GBW7_ANOCA Unreviewed; 237 AA.
AC H9GBW7;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000006626.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000006626.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000006626.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000006626.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004287};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004287};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; H9GBW7; -.
DR STRING; 28377.ENSACAP00000006626; -.
DR Ensembl; ENSACAT00000006772.3; ENSACAP00000006626.3; ENSACAG00000006778.3.
DR eggNOG; KOG2101; Eukaryota.
DR GeneTree; ENSGT00390000001280; -.
DR HOGENOM; CLU_117250_1_0_1; -.
DR InParanoid; H9GBW7; -.
DR TreeFam; TF332414; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000006778; Expressed in dewlap and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:1901981; F:phosphatidylinositol phosphate binding; IBA:GO_Central.
DR CDD; cd06880; PX_SNX22; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR15813:SF8; SORTING NEXIN-22; 1.
DR PANTHER; PTHR15813; SORTING NEXIN-22 AND 24; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..116
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 237 AA; 28005 MW; CE0E114EBC27F2E4 CRC64;
MQLEVRVPSA GLREAGQEEK PRTVFKVEIL CNGRKHSIEK RYSEFYALHK RIKKRCQVPD
FPPKHVPNWM TKVLEQRRQG LEAYLQGILL YNRWLPKEFL DFLKLWHFQQ DPKGDPLGVL
GDHDIFLEDN RQVALSYTCF VSTSKRESNS RAPEWFQVHN LWLCQRGQSD ALELSFKMFP
KASGFPPLGL CQEEKIGHLL LVFWAVLPTI SVHCRKRCQN IWRTSYWHIL STWDRQA
//
