ID   H9GEG6_ANOCA            Unreviewed;      1370 AA.
AC   H9GEG6;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Structural maintenance of chromosomes flexible hinge domain containing 1 {ECO:0008006|Google:ProtNLM};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000008677.3, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000008677.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000008677.3};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000008677.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   STRING; 28377.ENSACAP00000008677; -.
DR   Ensembl; ENSACAT00000008862.4; ENSACAP00000008677.3; ENSACAG00000008850.4.
DR   eggNOG; ENOG502QREW; Eukaryota.
DR   GeneTree; ENSGT00390000006950; -.
DR   HOGENOM; CLU_002288_1_0_1; -.
DR   TreeFam; TF329426; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000008850; Expressed in adrenal gland and 13 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR038892; SMCHD1.
DR   PANTHER; PTHR22640:SF2; STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR22640; UNCHARACTERIZED; 1.
DR   Pfam; PF13589; HATPase_c_3; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1303..1323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1370 AA;  155202 MW;  D4984DC9DFCC9D91 CRC64;
     MTCYLLHSID QLLPSATKER IDFIPHYDTL VKSGIYEYYA SEGQNPLPFA LAELIDNSLS
     ATSQNTGVRR IQLKLLFDDT QGKPAIVVID NGRGMSSKQL NNWAVYRLSK FTRHGDMERL
     GTYVRPPAVH HSLNSDISYF GVGGKQAVFF IGQSARMISK PAGSQDVHEL VLSKEDFEKK
     EKNKESVYSS YIRNRKLCDS SHIVNDDERF LHNLITEEED KKCFTAVVIT GVQPDHVHYL
     KNNFHLWIRQ LAHIYHYYIH GSKGNEINLP KKEGRPFSNI DIEISMFEKG KTPKIMNLRE
     IKDDMQTLYI STAADSFEFK ANVEGDGIVE GIIRYHPFLY EKETYPEDPC FPSNDEADCF
     AVERGARGKR PIFECFWNGR LIPYTTVEEF EWCAAPKKRG PTPIECYKRI SGVLFTNDKF
     QVSTNKLTFM DLEIRLKDKN TIFTRIVNGQ AQRMKIDREF ASWLKECHEK YDKQIKFSHF
     KGLITRPEVS SKRMQRPWAT YSAIEWDGKT YKVEQLVKSI KTVPIYHGSI QNFFLYGDHD
     GDVYAPGGFV QLALEPQALY DEIMVIPIHK LDRSASDTAL KRYIEEEMAR LPDKLSVTWP
     EGDELLPDET KLAGSTIGAL KVEILNKKGE PMQKLPGSRH GGSKKLLVEL KVILDSPTGN
     KEIISHISQH GNKWPFWFKK MENINKLGAY TLKLQVVLNE SNADIYAGRS LPSKTFKFNI
     IEGKPQKFSI GLLDPPFRVG LPFSIPLDVQ DEFVLHFVFI LLLKERHMAQ HSLSNFSLKI
     TLPGLKEESQ VLKIKLLPGP PCKLEVQPNS DILKTENGVA FPFHVKVLDK AGNLTAQPKL
     IVHCKFSGAP DLPVYTVDCS STGSNILTGN VLHVQNIKKE QIINAKIEIL SCKNVPPLEK
     TIKILPSSRV AKLQIFSVEG EKAIHIKHQD EINWIAGDVM QNLIFQMYDE GEREIKITPT
     LAEKIKVNWT PTIDREQLLN GFLPDVKVPT SVNDLRYNEV TFHDEHVSLG SGFTVRPLPD
     DPKHIKCRIK GSDKLQMCET LQSQIEVMIT DQHGNHIRNL TSSCVTSLGI SGNDLDKSSL
     KIVWQEDTQT ICVTGIRFKT CPPGIKELCF AWHEFSHFVR LNLVGGPPAK LLLIDWTDLE
     EPVPVINGKE LHKPLILQVC DQWNNPSSES NVRINLLKAS SVKITPSNLL LKTDENGRAN
     FGIVTIHAPR GEHVMQFKAL YNRNTLYCPV IKLNVLPDPE KPICLNVKYD KDAIFIAGST
     FPGKDKMVPE KVGTYSIQFL FAIDKTNALN SEQVCFLKNI MQIIFPLTVF WGSSLLCCVW
     LLLCASQPGL TICPSSLIIP RSWPVLSSHF GSSSVEGQGR ALTLQLNWIE
//