GenomeNet

Database: UniProt
Entry: H9GER1_ANOCA
LinkDB: H9GER1_ANOCA
Original site: H9GER1_ANOCA 
ID   H9GER1_ANOCA            Unreviewed;       374 AA.
AC   H9GER1;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   16-OCT-2019, entry version 43.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSACAP00000008878};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
OC   Toxicofera; Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000008878, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000008878}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000008878};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000001646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Proteomes:UP000001646};
RX   PubMed=21881562; DOI=10.1038/nature10390;
RA   Alfoldi J., Di Palma F., Grabherr M., Williams C., Kong L.,
RA   Mauceli E., Russell P., Lowe C.B., Glor R.E., Jaffe J.D., Ray D.A.,
RA   Boissinot S., Shedlock A.M., Botka C., Castoe T.A., Colbourne J.K.,
RA   Fujita M.K., Moreno R.G., Ten Hallers B.F., Haussler D., Heger A.,
RA   Heiman D., Janes D.E., Johnson J., de Jong P.J., Koriabine M.Y.,
RA   Lara M., Novick P.A., Organ C.L., Peach S.E., Poe S., Pollock D.D.,
RA   de Queiroz K., Sanger T., Searle S., Smith J.D., Smith Z.,
RA   Swofford R., Turner-Maier J., Wade J., Young S., Zadissa A.,
RA   Edwards S.V., Glenn T.C., Schneider C.J., Losos J.B., Lander E.S.,
RA   Breen M., Ponting C.P., Lindblad-Toh K.;
RT   "The genome of the green anole lizard and a comparative analysis with
RT   birds and mammals.";
RL   Nature 477:587-591(2011).
RN   [3] {ECO:0000313|Ensembl:ENSACAP00000008878}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AAWZ02025844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 28377.ENSACAP00000008878; -.
DR   Ensembl; ENSACAT00000009069; ENSACAP00000008878; ENSACAG00000009067.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00970000193347; -.
DR   InParanoid; H9GER1; -.
DR   OMA; PCMSLEK; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000009067; Expressed in 1 organ(s), highest expression level in skeletal muscle tissue.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IBA:GO_Central.
DR   GO; GO:1990573; P:potassium ion import across plasma membrane; IBA:GO_Central.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001646};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     42     64       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    119    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        8    147       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      154    325       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      353    374       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   SITE        133    133       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   374 AA;  43354 MW;  EF3C7CDCAC08F24B CRC64;
     KQQRQRYVTK VGKCQVNLGN IQEKKRFLSD IFTTIVDLKY RWFLFVFSMC YIITWVAFGV
     IYYFDSWIRD DVNHIGDPDW KPCIENLDNF ISALLFSVES QRTIGYGSRI VTANCTEGVI
     LLMAQSIIGS MIDALMVGCM FVKISRPKKR AQTLIFSKKC VISHRDDQLC LMFRIGDLRD
     SHMVDAKIRA KLIKSRQTKE GEFIPLEQSE LNLGYDTGED RLFLVEPQII CHVINEQSPF
     WEMSAEALKR EQFEIIIILE GIVEATGMTC QARTSYVEDE ILWGYRFEPC MSLEKGAFRV
     DYTRFEKTFE VQTPVISARE MYEQKEMENR DQSTLSLYWD HLVHPCFSAE LNNESRQGDG
     PSEAGISRLG FSNI
//
DBGET integrated database retrieval system