ID H9GGM5_ANOCA Unreviewed; 699 AA.
AC H9GGM5;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Zinc finger and BTB domain containing 45 {ECO:0008006|Google:ProtNLM};
GN Name=zbtb45 {ECO:0000313|Ensembl:ENSACAP00000010457.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000010457.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000010457.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000010457.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000010457.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003224562.1; XM_003224514.3.
DR AlphaFoldDB; H9GGM5; -.
DR STRING; 28377.ENSACAP00000010457; -.
DR Ensembl; ENSACAT00000010673.4; ENSACAP00000010457.3; ENSACAG00000010650.4.
DR GeneID; 100564999; -.
DR KEGG; acs:100564999; -.
DR CTD; 84878; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000160859; -.
DR HOGENOM; CLU_019055_0_0_1; -.
DR InParanoid; H9GGM5; -.
DR OrthoDB; 2882771at2759; -.
DR TreeFam; TF335684; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000010650; Expressed in hemipenis and 10 other cell types or tissues.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0001817; P:regulation of cytokine production; IBA:GO_Central.
DR GO; GO:0002682; P:regulation of immune system process; IBA:GO_Central.
DR CDD; cd18229; BTB_POZ_ZBTB45; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR46105; AGAP004733-PA; 1.
DR PANTHER; PTHR46105:SF23; ZGC:76872; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 31..94
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 490..517
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 518..545
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 546..573
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 573..600
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 121..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..140
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 75610 MW; 5F91681F40944EF5 CRC64;
MAEAVHYIHL QNFSKSLLET LNGQRLGGHF CDVTVHIQEA TLRAHRCVLA AGSPFFHDKL
LLGYSEIEVP PVVPSQVVRQ LVEFMYSGSL VVAQSEALQI LTAASILQIK TVIDECTQII
SQSRSPKPPT APPPVSLSIP RVLPAKPQEQ LTSKEAIASV SRPSDIEATH LEAPKLLCAS
EVRYKLRDLL SSQHREARGA TCEGGISDGE AGGAYLHPAE ATPSCHSRKQ RQPVRLQLSE
VMPVIIKDEE EAGRESREGV VATTATSEPE GKLSCFAECG GSTNFPAGFP DETDTKNSGN
TSGANRKESI HMDYATAEGQ DFFGNQDVFS ESFIPSWQGE ESNEEATASV TRDREKFHSD
CGLEISNLRS LAGEFKPDLG GPSSAFPPRS TNSGGGLAFV SSLGIQRELK PEVSSANAAT
STTSIFQFHL PQPSGVAQSF YSIQQQPQQQ DAGGTNMVQL GPSNMGSGAM HGGEQQNQQP
GPSRCSEPSY QCSHCQKTFS SRKNYTKHMF IHSGEKPHQC SICWRSFSLR DYLLKHMVTH
TGVRAFQCSI CCKRFTQKSS LNVHMRTHRP ERFQCCICNK YFSHRTLLER HMTTHTAWKG
GQPEAPGAMA PTTSSTDWKE KPNVAGTVPA IEGNVAGTTT AWKTGEPSAE SAIVAWKAGD
PAPGDGNLVG WKGETTGEGS VAAWKGDPAS EASMQPHTA
//
