ID H9GH12_ANOCA Unreviewed; 609 AA.
AC H9GH12;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000010751.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000010751.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000010751.4};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000010751.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; H9GH12; -.
DR Ensembl; ENSACAT00000010974.4; ENSACAP00000010751.4; ENSACAG00000010950.4.
DR eggNOG; ENOG502QQ5W; Eukaryota.
DR GeneTree; ENSGT00940000163299; -.
DR HOGENOM; CLU_258747_0_0_1; -.
DR InParanoid; H9GH12; -.
DR TreeFam; TF329295; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000010950; Expressed in ovary and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 5.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 5.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 5.
DR SUPFAM; SSF56487; SRCR-like; 5.
DR PROSITE; PS00420; SRCR_1; 2.
DR PROSITE; PS50287; SRCR_2; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 494..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..87
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 90..177
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 180..280
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 282..382
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 384..484
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 12..76
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 25..86
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 56..66
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 167..177
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 205..269
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 218..279
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 249..259
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 307..371
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 320..381
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 351..361
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 409..473
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 422..483
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 453..463
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 609 AA; 66524 MW; F4B3DFF31FBD4B48 CRC64;
MLSHNMEWWT VCDASWDIHD AQVVCRQLGC GNASKVLIGA HYGQGTGPIW LKGVNCTGEE
ASLSECSQSP HEEYNCDHSR DAGVECTGQF RLVNGSSHCS GRVEVFYNKH WEAICDKDLK
SDEAQFVCMK VGCGKMLSAP KGSHFGRGHS IVRLTLHFWG DIEEKNCVGG EAAAVICSEV
KLIGDPDYCY GRVEVLHNQT WGTVCDDSWN LKSAQVVCRE LDCGEALAAP GGAHLGAGYG
PIWLFDAECQ GNEMSFRYCD LNALEEHSCT HEEDAGVICA RTRLVNGPNR CSGRVEMLLN
GLWGTVCDDG WDLSDAQVVC RELGCGEAVS APEGAHFGKG NGTIWIHNAE CLGTEVALWD
CKKAMHESYE CRHEEDAGVV CSDLHLMNGT SPCSGRVEVF HNDAWGTICD AGWDLQDAQV
VCSQLGCGKA SKALGGAHYG QGSGPIWLES INCTGEEASL KECQKGGWGE HSCSHSQDAS
VECSAVESSV ETSVHLGVAA LVFLALVVIV AEAGCGKMWQ EEEEEEERAA TLSSPLNWPV
LVIKIHLQVL WSYSQKEFHV KSKFKGMYFE IYLSHYNNVS FYTYMLLLKM VNVLLGIVGF
VMFFILSVC
//
