ID H9GIX7_ANOCA Unreviewed; 1451 AA.
AC H9GIX7;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Sorbin and SH3 domain containing 1 {ECO:0008006|Google:ProtNLM};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000012232.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000012232.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000012232.4};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000012232.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 28377.ENSACAP00000012232; -.
DR Ensembl; ENSACAT00000012482.4; ENSACAP00000012232.4; ENSACAG00000012338.4.
DR eggNOG; KOG4225; Eukaryota.
DR GeneTree; ENSGT00940000158658; -.
DR HOGENOM; CLU_003951_1_1_1; -.
DR InParanoid; H9GIX7; -.
DR TreeFam; TF320680; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000012338; Expressed in testis and 12 other cell types or tissues.
DR GO; GO:0030055; C:cell-substrate junction; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0031589; P:cell-substrate adhesion; IBA:GO_Central.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 200..258
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 1106..1165
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1180..1241
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1390..1451
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1451 AA; 163923 MW; 74DB51886C2310E4 CRC64;
MTSEPKEVDV GNTVVNGLMP STNGQKRDVD TAKVCTGKGA VTLWASPAHE ENLNTSYTSS
QDIQLSESAE PGKQEIDDIL PSVGSNTDAQ SSPLAAKGYR SVRPNFFEST SHEPCPQLYE
APRTSSGTEC YGPLTVASKH SSAYPSTTIV NPTIVLLQHN REQQKKLSNR AESVPDAPVL
DKVDSIPTQE KISQWKKQDG TRVTEYEADH SLDDIGIPLR NTDRSKDWYK TMFKQIHRLT
KDTPEENPYC PTYIFPELPD IQSQAKEENP YYPTYQFPVS TPSPKSEDED SDSCVPQYSF
YKDTRSQNSV PRSKSENDTN TPEKVVRRSA TLPLPARSSS LKGSVERNDW EPPDKKVDTR
KYYAEPKSIY EYQPGKSSFL DNEHLTRDIS LEEIDLKDEP WYKFFSELEF GKPTDPEKEL
YLYRTELEAD TEKIENLDKV PDKEPVKSTA HSSSMEILSD HLAHSPYSPN SHLVQREFTD
TIGDSTGLET ERQIYKSVLE GGDIPLQGLS GLKRPSSSAS TKVDRKGGNA HTIARSSVYN
QSFNFSNAGQ LGQFCKYKKP LSVAKVCIAE ILPSKFKPKR ATPPIPRLDK KDLLPHEKTQ
SCENLHSSLT FFGNKKNSVI DVDASFENIL MKSKQQSAVK SSSTQSLREC GSSSFRKEYM
LGSQKNSMEF AMLYKDMHHI NRSGFQRGVI SSGSVKEIAS HFECEFKSKR EPSLSPNREN
LEQIPKHTVS SRITAFEMLI QKSLSMPALS FSSTHNKSPT PSLSNSCLNS IYSAEYELDL
SMPVLREKNL SDLTNLADTS SHSYSNIEDT SSEFSNMTPI DTLSACPDEI DVISNKSNDS
GGDSSISIAQ KYKVNKCKGS CPASYTRFTT MRRHEQQQPA QGDVEGEKHL LPRNIYLMSP
LPFRLKKPLQ RHSRTTLPLP GLGALLASTC EIQNDQSRGS HSNNTSFYEL CMQRKPPAPK
RLSSCDIVKR FSHFLEVETW QTSSVSLLDF PDVFNNANVP YALYYKVDTN NNPQKEFRTY
PGDSESPRHF PPLDYMENPE DIFHRRHSDK EKLLEDQRRL KREQEEADIA ARRHTGVIPT
HHQFITNERF GDLLIVDDTA KRKSGSEMRA ARARFDFKAQ TLKELPLQKG DIVYIYKEID
QNWYEGEHHG RVGIFPQSYV ELLPPREKHQ PKKPSQLQVL EYGDAIAKFN FNGDTQVEMS
FRKGERITLI RQVDENWYEG KILGTNRQGI FPVTYVDIFK QPVVKNMEDH SDLLFSHSMN
HSQATSPQSA NAKAFYPSAL LSPSAIPSFA VRTELPPRLS CRVNMPQPSH HSLRPGPDLT
ESEKTYVETV CNEILNIAEK SVHYCSTISQ PLVSCHKGPF SDSRSSLIIS QQPPKVPLLE
STIERNHTAQ NVLSYRALYS YIPQNDDELE LRDGDIIDVM EKCDDGWFVG TSRRTQQFGT
FPGNYVKLLS L
//
