ID   H9GMJ2_ANOCA            Unreviewed;       812 AA.
AC   H9GMJ2;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=ABC-2 type transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF12698};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000015356.3, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000015356.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000015356.3};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000015356.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; H9GMJ2; -.
DR   STRING; 28377.ENSACAP00000015356; -.
DR   Ensembl; ENSACAT00000015669.4; ENSACAP00000015356.3; ENSACAG00000015547.4.
DR   eggNOG; KOG0059; Eukaryota.
DR   GeneTree; ENSGT00940000154658; -.
DR   HOGENOM; CLU_000604_19_0_1; -.
DR   InParanoid; H9GMJ2; -.
DR   TreeFam; TF105191; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000015547; Expressed in hemipenis and 6 other cell types or tissues.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR   GO; GO:0006869; P:lipid transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR013525; ABC2_TM.
DR   InterPro; IPR026082; ABCA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR   PANTHER; PTHR19229:SF49; PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7; 1.
DR   Pfam; PF12698; ABC2_membrane_3; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        507..527
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        547..571
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        583..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        610..630
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          507..708
FT                   /note="ABC-2 type transporter transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF12698"
SQ   SEQUENCE   812 AA;  90112 MW;  15507FF73BBFFBB0 CRC64;
     MGNEGRSAPT LQLKALLKEN ESFSQFLRTN ASFPPDLVDE LLASRLNLRV FSLAGMPLKR
     IVCNASLLSE FLAAPNAGAA ERVQQGLCAL PEATLEALER RFSLEADWVK VLADRLGSGS
     VDIANAVDAF RLFLRGIEPL AKEVSSFSSF ADFRDNLRAF SGPSPASAFA SVSRIFCGDP
     DRGGLKIPSL NWYEDNDVRS FLARNGSART SIPLGNSSSS FCQDLVQSLE SSPLTRILWR
     GIKPLFVGKI LYAPSTPSTR KVMAEVNRTF QNLAVLRDVK GAWDELGPRV YTFMNASLEL
     GAIQSLLDTP GVVQLLEQQL QGTSWNLTTI KEFLSPDAES PGYTWHKAYA AVDSGIRTLS
     QFTECVSLDK IEAAASEDQL VERALQLLDD RRFWAGVVFL PPDNRSKLDS DLPRHVRFKI
     RMDIDDVTRT NKIKDRFWDP GPAADPFNDL RYVWGGFVYI QDLVEQAISR VLAGPLSPQR
     RMGVYVQQMP YPCYVDDIFL RVLNRSLPLF MTLAWIYSVA MIVKGVVHEK EARLKETMKI
     MGLSNGILWL SWFLSSFIPF LISSALLVLI LKVGDILPYS DPAVVFLFLA AFAVATISQC
     FLISTFFSRA NLASACGGIV YFSFYLPYVL CVAWRDRITF PLRLFASFLS PVAFGFGCEY
     FSLYEEQGVG IQWQNLNASP VEGDRYTFAT SGGLLLLDAL LYGVATWYIE GVFPGQYGIP
     KPWNFPILKS YWFGESSTNG SPHPIPTSVF NSTKAIVEDP PTQFKVGVSI RNLVKIYHSS
     SKIAVNGLSL DFYEGQITSF LGHNGAGKTT TM
//