ID H9GP31_ANOCA Unreviewed; 4637 AA.
AC H9GP31;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=LDL receptor related protein 2 {ECO:0000313|Ensembl:ENSACAP00000016930.4};
GN Name=LRP2 {ECO:0000313|Ensembl:ENSACAP00000016930.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000016930.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000016930.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000016930.4};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000016930.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LDLR family.
CC {ECO:0000256|ARBA:ARBA00009939}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 28377.ENSACAP00000016930; -.
DR Ensembl; ENSACAT00000017265.4; ENSACAP00000016930.4; ENSACAG00000017153.4.
DR eggNOG; KOG1215; Eukaryota.
DR GeneTree; ENSGT00940000157232; -.
DR HOGENOM; CLU_000085_1_1_1; -.
DR InParanoid; H9GP31; -.
DR OrthoDB; 2876235at2759; -.
DR TreeFam; TF315253; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000017153; Expressed in kidney and 6 other cell types or tissues.
DR GO; GO:0016324; C:apical plasma membrane; IBA:GO_Central.
DR GO; GO:0030424; C:axon; IEA:Ensembl.
DR GO; GO:0031526; C:brush border membrane; IEA:Ensembl.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:Ensembl.
DR GO; GO:0030425; C:dendrite; IEA:Ensembl.
DR GO; GO:0030139; C:endocytic vesicle; IEA:Ensembl.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0005768; C:endosome; IEA:Ensembl.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0043235; C:receptor complex; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR GO; GO:0042562; F:hormone binding; IBA:GO_Central.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:Ensembl.
DR GO; GO:0035904; P:aorta development; IEA:Ensembl.
DR GO; GO:0008283; P:cell population proliferation; IEA:Ensembl.
DR GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl.
DR GO; GO:0034311; P:diol metabolic process; IEA:Ensembl.
DR GO; GO:1904447; P:folate import across plasma membrane; IEA:Ensembl.
DR GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR GO; GO:0030001; P:metal ion transport; IEA:Ensembl.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR GO; GO:0140058; P:neuron projection arborization; IEA:Ensembl.
DR GO; GO:0003148; P:outflow tract septum morphogenesis; IEA:Ensembl.
DR GO; GO:0043491; P:phosphatidylinositol 3-kinase/protein kinase B signal transduction; IEA:Ensembl.
DR GO; GO:0070447; P:positive regulation of oligodendrocyte progenitor proliferation; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0061156; P:pulmonary artery morphogenesis; IEA:Ensembl.
DR GO; GO:0006898; P:receptor-mediated endocytosis; IBA:GO_Central.
DR GO; GO:0044321; P:response to leptin; IEA:Ensembl.
DR GO; GO:0003139; P:secondary heart field specification; IEA:Ensembl.
DR GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR GO; GO:0060068; P:vagina development; IEA:Ensembl.
DR GO; GO:0003223; P:ventricular compact myocardium morphogenesis; IEA:Ensembl.
DR GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
DR GO; GO:0042359; P:vitamin D metabolic process; IEA:Ensembl.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00112; LDLa; 33.
DR Gene3D; 2.10.25.10; Laminin; 7.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 36.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 8.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR22722:SF11; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2; 1.
DR PANTHER; PTHR22722; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00057; Ldl_recept_a; 35.
DR Pfam; PF00058; Ldl_recept_b; 15.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 20.
DR SMART; SM00179; EGF_CA; 10.
DR SMART; SM00192; LDLa; 36.
DR SMART; SM00135; LY; 36.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF57424; LDL receptor-like module; 35.
DR SUPFAM; SSF63825; YWTD domain; 8.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 7.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS01209; LDLRA_1; 16.
DR PROSITE; PS50068; LDLRA_2; 36.
DR PROSITE; PS51120; LDLRB; 23.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 4405..4429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 412..454
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 455..497
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 498..544
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 545..589
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 772..813
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 814..857
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 858..901
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1459..1501
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1502..1544
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1547..1590
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1771..1813
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1864..1911
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1912..1953
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2183..2226
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2227..2270
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2500..2543
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2544..2585
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3220..3262
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3314..3357
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3358..3400
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 3947..3987
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 4135..4177
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 4178..4221
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 4223..4264
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 4358..4392
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 4502..4559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4582..4604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 7..19
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 14..32
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 26..41
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 87..99
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 94..112
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 106..121
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 131..149
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 143..158
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 162..174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 169..187
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 181..196
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 201..213
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 208..226
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 220..235
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1002..1014
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1009..1027
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1021..1036
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1043..1055
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1050..1068
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1062..1077
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1085..1097
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1092..1110
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1104..1119
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1125..1137
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1132..1150
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1144..1159
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1183..1198
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1247..1259
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1254..1272
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1266..1281
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2681..2693
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2688..2706
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2722..2734
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2729..2747
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2741..2756
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2769..2787
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2845..2857
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2852..2870
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2887..2899
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2894..2912
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2974..2986
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2981..2999
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2993..3008
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3013..3025
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3020..3038
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3056..3068
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3063..3081
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3075..3090
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3534..3546
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3541..3559
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3575..3587
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3582..3600
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3616..3628
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3623..3641
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3680..3695
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3708..3726
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3720..3735
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3740..3752
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3747..3765
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3759..3774
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3779..3791
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3786..3804
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3798..3813
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3823..3835
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3830..3848
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3872..3890
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3909..3921
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3916..3934
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3928..3943
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 4382..4391
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 4637 AA; 518832 MW; DEA660F68FD8EB91 CRC64;
LFSPFGCESG QFRCGNGRCI PAEWRCDGAR DCSDDTDEAG CPRPTCGGSQ FQCLSDGECI
PRSWVCDDEE DCEDGSDEHQ QCPGRTCSSQ QFTCTNGQCI PGTYRCDRVK DCMDETDERG
CQYPTCDQLS CSNGACFNAS QHCDGKLDCR DASDEANCTR GCSNAQFQCG NGECIPRAFL
CDHDDDCGDR SDENSCTYAT CKGNFYTCPS GRCIHQSWIC DGDDDCEDNA DEIGCESGHR
DCYPGEWACP TSGQCIPIGK VCDGTPDCPA GEDETNITAG RLCNISRCAA LSCQYRCHSS
PSGGTCFCPA GFVISSNDSR TCVDFDDCKM WGVCDQVCED RVGHHQCRCV EGYVLEHHRH
CRANTSSGVA SVIFSNGRDL LVGDLHGRGF RTLVQSRNRG VAVGVDFHFQ LRRIFWTDTV
QDKVFSVRID GTDIHEVLNV SVDTPENLAV DWINNKLYIV ETSVNRIDMV NLDGTNRVTL
IAESLGNPRG IAVDPTIGYL FFSDWDSLSG DPKVERAFMD GTNRLDLVKT KLGWPAGITL
DIVSKRLYWV DSRFDYIETV TYDGLQRRTI AHGGSLIPHP YGISLFEHNL YFTDWTKMAL
MKANKFADSN PQVIYQSSLR PYGVTIYHAL RQPYVRNPCS GNNGGCDQIC VLSHRTDNDG
LGYRCKCMLG FDLHADGRRC VAVQQFLLFS SQLAVRGIPF NLSTQEDVII PVTGSPSYFV
GIDFYAQEDT IFYSDTTKDI IYKQKTDGTG KEILAANRVE GVEDLCFDWI SKNIYWTDPR
YRSISVMRLA DKSRRAIVQN LNNPRSIVVH PVIGYIFWTD WYRPAKIMRA WSDGSHAMPI
VNTTLGWPNG LAIDWSSLRL YWVDAFFDKI EHSTFDGLDR RTLERISQMT HPFGLTIFGG
YAYFTDWRLG GIVRVRKTDG GEMTIIRRGI NNIMHVKAYN AHFQTGNNYC NRATNPNGDC
SHFCFPVPNF QRVCGCPYGM KLSSNQLTCV EDPSNEPPTL QCGAYSFSCG NGRCVPRFYQ
CDGVDDCHDN SDEQNCGSLN TSCATSAFTC RNGQCIPRRW RCDKHNDCLD NSDELHCPTQ
GPTSCPATLF TCDNGKCIPR IWMCDTDNDC GDGSDEKNCT FTETCEPGQF QCPDHRCIDP
FYVCDGDKDC IDGADEHDCI YNCSSTEFKC ASGDQCISNY YQCDGVFDCN DHSDEVNCPT
RPPGMCHQNE FQCQSDGNCI PANWECDGHP DCVDGSDEHH RCPPRTCPPT LFRCDNGNCI
YRAWVCDGDN DCRDMSDESD CPTPPFRCPS WQWQCPGHSM CVNLSKVCDN LSDCPNGADE
SPLCNEPQPD QETCSDNNAG CTHECIQGPF GAQCSCPFGY QLANDSKTCE DINECDPPGF
CSQHCHNERG SFRCYCDEGY VLEPNGKTCK VAEPGYLLLL VASRNQIVAD NITSHAQRIY
SLVRDGRNIV AIDFDSVTER IFWSDITQDK IWSAYQNGTD RKVVFDSGVT VTESIAVDWI
GRNLYWTDYV LETIEVSRLD GTHRTVLISE NVTNPRGLVL DPRTDAHVMF WTDWGRNPRI
ERASMDGTLR TTIVSSKIYW PNGLSIDYPN KLLYFADAYL DYIDFCDYNG NNRRQVVASD
LVLRHPHALT LFEDFVYWTD RYTHRVIRAN KWNGRNQTVL IYNVNQPLGI TAIHPVKQPA
GDNFCAQSAC SHLCLLSSSG PRFYSCACPS GWILSPDHVN CMRVEEPFLI AVRDNIIYGI
SLNPEEKTND AMVPIAGVQN GYDADFDDSE QMVYWVENPG EIHRVKSDGT NRTTFAPAAV
IGTPVGLAVD WISGNLYYSN PNTQSIEVLK LRSEVIYRKT LITNDGTSSG SGKPIGLTVD
PINGKLYWTD QGTDSGVPAK IASANMDGSD IRTLFTGNLD HVGFITIDIK EQKLYWSVSS
TGVIERGNVD GTNRMTVVVH LSRPWGVAVY GSYLYYTDRD YEVIERVDKA TGANKVVLRD
NISGLKCLRV YYRDNSGGTS NGCSNNVGVC QHLCLPVPGG LFSCACATGF RLNPDNRTCS
PYSSFVVVSM LSAIKGFSLE TSDHSEAMVP MAGRGRNALH VDVHMPSGFI YWCDFTSRVP
SQNAIRKIKP DGSYFRNVIT SGIGLNGIRG IAIDWVADNL YFTNAFVAET FIEVLRLNTT
YRRVLLKTTI DMPRHIVVDP KNRYLFWADY GQNPKIERAL LDCSNRTVLV SEGIVTPRGL
AIDHSTGYVY WVDDSLDMIA RISHDGGEPE IIRYGSRYPT PYGITIFENS MIWVDRNLKK
IFQASKEPGN TEPPTAIRDN INWLRDVTIY NNHYQSRSPS DVNFNPCLEN NGGCSHLCFA
IPDQQTPRCG CAFGVLENDG KRCSISTDNY LIFALENALR SIHLDPDDHS PPFRTMTVTR
TAVALDYDSV NNIIYFTQSS PAGTGRISYI SIYSGTGNPT LVASDLGTPD GIAFDWMNRR
LYYSDYLNQT ISSMAVDGSN RSVVARVPRP RAIVLDPCQG YMYWTDWSTS AKIERATLGG
NFRTAIISTN LVWPNGLTLD YEDQQLYWAD ASLQKIERSS ITGENREVII STALYPFAMT
LFDQHIYWTD WNTRSIYRAN KYDGSDQIVM ISSLPTRPMD IHVWSKSKQR QCTNPCNQFN
GGCSHICVSG PTGAECQCPS EGHWYLANNN KHCVMDNGTR CAGGFFTCLN GRCISERWKC
DNDNDCGDDS DELESVCAFH TCQPTAFTCG NGRCVSYAYR CDHYNDCGDN SDEVGCLFRT
CDSNREFTCN NGRCISLEYV CNGVNNCYDN GTSDERNCPE RTCQSGYTKC QSTNICIPRT
YLCDGDNDCG DMSDESPTHC VSLTCTSSEF RCSSGRCIPA HWYCDQAIDC ADSSDEPSSC
VPPVRSCSSD QFRCDDGRCI PATWICDGDN DCGDMSDEDQ RHSCANRTCS ASEFTCVNNA
PPLRRCIPRA WVCDGDADCS DAYDEHQNCT RRPCMDHEFT CSNGLCIRNT YRCDRRNDCG
DSSDERSCIY QPCPQHQFTC QNGRCISKAY ICDGDNDCGD ESDELEHLCV TPEVTCPPHH
FKCDNGNCIE VAKLCNRVDD CLDNSDEKGC GINECNDSSI SGCDHVCTDT LTSFYCSCHP
GYRLMSNKRS CDDVDECSET PSVCSQICEN SVGSYICKCA PGYIREPDGK SCRQNSNISP
YLIFSNRYYL RNLTTDGQSY SLILQGLRNV VALDFDRVEK RLYWIDVGRK VIERMFFNGT
SKETIISDGV PSGEGIAVDW VGRKLYWVDD SKDCLYVSEL DGRFRKKLID RCLDPNSTFC
FQYPRAVVVH PKYGQVFWTD WAERAYIGRV GMDGKNKTVI ISAKLEWPNG LTIDYTNDKL
YWADAHLNYI EYSNLDGQHR HTVYDGTLPH PFAITIFEDT IYWTDWNTRT VEKGNKYNGS
GRTVLVNTTH RPFDIHVYHP YRQPVVRNPC GTNNGGCSHL CLIKNGGNGY SCECPDNFMV
VQFGDLAHCL PMCSSTQFLC ADSERCIPIW WKCDGQRDCR DGSDEPSTCP HRYCPVGQFQ
CNDGNCTSSH YLCNGLSDCP DGADEDHVLC ANHQCESHQW QCDNKRCIPE AWQCDREDDC
GDNSDEDSSH CASRTCPPGQ FKCDNGRCIP QSWKCDVDDD CGDNSDEPVH ECMGPSYRCD
NHTEFSCRTN YRCVPLWAVC NGHNDCRDNS DEQGCETRTC DPLGDFRCDN HRCIPLRWKC
DGDNDCGDES DEQNCSPREC TESEYRCDNL RCIPSRWICD HDNDCEDNSD ERDCELRTCH
PGYFQCDSGH CVAERFRCDG SADCLDFSDE AACPTRYPNG TYCPRTMFEC KNHVCIQPYW
KCDGDDDCGD GSDEELHFCL DIACEPPFRF RCGNNRCIYS HELCNQKDDC GDGSDEKEEH
CREPTPKPCT TEEFKCGNGN CIPLHYVCDN YDDCGDHFDE LGCNSGTGRT CTENICEHNC
TNLTEGGFIC TCRPGYRPND LNRNNCEDIN ECDIFGTCPQ VCQNTKGSYE CFCAEGFRSV
GDQQGKQCAA NGNPPILLLP DNVRIRRYNM SSEQYSDYIE NEEHIQAIDY HWDPEGIGLS
VVYYSILGRG SEFGSIKRAY IPTFESSGNN PVKEVDLNLR YLVSPVGLAV DWVGRHLYWT
DAGTNRVEVA KLDGRYRKWL IYSQLDQPAA IAVNPKLGLM YWTDWGRQPK IESAWMDGQQ
RQILVSEDLG WPTGLSIDYL NGDRIYWSDQ KENLVESMKF DGTDRKTILH GVSSPYSLDV
FEGHLYWISK ERGEVWKEDK FGKGEKVKVL TINPWLTQVR IYHQHRCNQS VSNPCKDVCS
HLCLLRPGGY SCACPQGARF VEGSTTECDA AIESPPTMPP ACRCMYGGTC YFDESGLPKC
KCAYGYMGNY CEAGLSKGVP PATTAVAVLL TVILIIVIGA LGVGGFFNYR RTGSLLPSLP
KLPSLSSLVK STENGNGVTF RSGADVTMDI SVSGFGAETA IDRAMQMNEN FAVESGKQPI
TFENPMYTTK DGGTGDVNTA PPTQVAASSS EGNESFENPV YSTPLSASAT QPPASTEIAQ
ESKWSIFKRK LKQSTNFENP TYSEMEKEQQ GEAVSVPPPS PSLPQKIILR RDQPLAFTAT
EDSFKDTANL VKEDSVV
//
