ID H9GP83_ANOCA Unreviewed; 438 AA.
AC H9GP83;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Transmembrane channel-like protein {ECO:0000256|RuleBase:RU310713};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000017069.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000017069.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000017069.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000017069.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU310713}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU310713}.
CC -!- SIMILARITY: Belongs to the TMC family. {ECO:0000256|ARBA:ARBA00006510,
CC ECO:0000256|RuleBase:RU310713}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU310713}.
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DR AlphaFoldDB; H9GP83; -.
DR STRING; 28377.ENSACAP00000017069; -.
DR Ensembl; ENSACAT00000017404.3; ENSACAP00000017069.3; ENSACAG00000017340.3.
DR eggNOG; KOG1075; Eukaryota.
DR GeneTree; ENSGT01050000244894; -.
DR HOGENOM; CLU_1247782_0_0_1; -.
DR InParanoid; H9GP83; -.
DR Proteomes; UP000001646; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR038900; TMC.
DR InterPro; IPR012496; TMC_dom.
DR PANTHER; PTHR23302:SF4; TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR23302; TRANSMEMBRANE CHANNEL-RELATED; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF07810; TMC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU310713};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU310713};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU310713}.
FT TRANSMEM 282..307
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU310713"
FT TRANSMEM 328..353
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU310713"
FT TRANSMEM 398..420
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU310713"
FT DOMAIN 1..107
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 438 AA; 50813 MW; 046278285B4D5DE6 CRC64;
MILHLVDGKL PTGVEIIYRT DGKLFNLSRL KAKTKVTTTS VIELQYADDN VVCAHSEEDL
QATLNTFTEA YEKLGLSLNI EKTKVLFQQA PATPSAKPGI QLNGVTLENV NHFRYLGSHL
STKVNIDTEM QHRLNSASVT FFRMKQRVFD DRDIRRDTKV LVYKAIVLPT LLYACETWTV
YRHHTKLLER FHQRCLRKIL LGLLCYHWLS QEVTSSKIQC WETFVGQELY RLVVMDFIFT
LLDTFFGDLM WRVILEKKLQ RKQRPEFDIA RNVLELIYGQ SLTWLGVFFA PLLLAVLILK
LLLLFYIKEA SLKRNCQSPN KPWHASHMDT VLITLLCFPT FLGASIFLSY TIWAVKPSEM
CGPFQIFETI YDSGKTWIVD LEQSCPNLTW FTWIQQHLIQ NSFFLFLISG ILLAVIYLNI
QVVKGQRRII TLQMILDG
//
