ID H9GUD6_ANOCA Unreviewed; 1668 AA.
AC H9GUD6;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN Name=rreb1 {ECO:0000313|Ensembl:ENSACAP00000020642.2};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000020642.2, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000020642.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000020642.2};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000020642.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008116157.1; XM_008117950.2.
DR RefSeq; XP_008116158.1; XM_008117951.2.
DR RefSeq; XP_008116159.1; XM_008117952.2.
DR RefSeq; XP_008116160.1; XM_008117953.2.
DR RefSeq; XP_008116162.1; XM_008117955.2.
DR RefSeq; XP_008116163.1; XM_008117956.2.
DR RefSeq; XP_008116164.1; XM_008117957.2.
DR STRING; 28377.ENSACAP00000020642; -.
DR Ensembl; ENSACAT00000027663.3; ENSACAP00000020642.2; ENSACAG00000000520.4.
DR GeneID; 103280098; -.
DR KEGG; acs:103280098; -.
DR CTD; 6239; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000157533; -.
DR HOGENOM; CLU_002702_0_0_1; -.
DR InParanoid; H9GUD6; -.
DR OrthoDB; 5398957at2759; -.
DR TreeFam; TF332503; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000000520; Expressed in hemipenis and 11 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR46451; RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR46451:SF1; RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR Pfam; PF13894; zf-C2H2_4; 1.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00355; ZnF_C2H2; 16.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 15.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 48..75
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 79..106
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 107..134
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 192..214
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 300..327
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 615..642
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 643..670
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 671..694
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 725..752
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 756..786
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1155..1182
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1347..1374
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1470..1497
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1498..1525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 16..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 127..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1008..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1363..1468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1518..1637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1035
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1234..1268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1289..1311
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1365..1383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1419..1468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1525..1551
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1552..1581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1583..1597
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1668 AA; 185087 MW; 7B14B2DECAC0B12A CRC64;
MMAAVMSLGK IAENGTAATQ NIKSPSKPLA PNRIGRRNQE TKDDKSSYIC PLCEKVCTTQ
HHLTMHIRQH NTDTGGTDHA CSICGKSLSS ASSLDRHMLV HSGERPYKCS VCDQSFTTNG
NMHRHMKIHE KDPNSTTSTP VPASPLKRRR SSAKRKLSQD HEADKEERTP AKKQVVEESQ
SGEAEKKAEE VYRCPVCFKE FSCKYGLESH MEAHPDTSLR CDVCCITFRT HRGLLRHNAV
IHKLLPKDPT GKPFIQNNPS IPAGFHDLGF TDFSCKKFPR ISQVWCETNL RRCTSEFHRY
VCEMCNKAFP MRSALKLHTE THATDQGKEE HKLQSEDADL KAYMESLGLR HTKDVESAKQ
EELAPDDEVQ ETQLRTLKCN LPQEPGNASQ LNVSPLETAA VGGPFSVLSS TKENIKLLSL
QPFQKGFIIQ PDNSIVVKPI SGELADIQQI LKMASSATPQ ISLPQLSKTS HIPVQSIFKH
MPPLKPKPLV APRTVVATST PPPLVNTQQA SPGCISPSLP PVPPKLVLPS EESTSNSHLP
PSKSGAKPSP SDQEKMEPVN QHEIRIQLEQ DSIIEALLPL TMEAKIKQEV TERDFKAIIT
GTANKKTPAM RKVLYPCRFC DQVFPFSGVL RAHVRSHLGI SPYQCNICDY IAADKAALIR
HLRTHSGERP YICKICQYPF TVKANCERHL RKKHLKATRK EIEKNIEYVA SNAAEMVDAF
CSPDTVCKFC GEDLKHYRAL RIHMRAHSGC QKKKPFECKE CGTAFSAKRN CIHHLLKQHL
HIPEREVESY VLAVECQPPE TQPGSLQLLE GSTYTDCKPI TPFMESQNGV LRGTPSHASI
KLETANSFPR NFDEPLDFSQ KNKNLNSVLI KQENPFDSSF YDCSMEPIDL SIPKASKKEN
ENSLNEEKKQ EPFDGHEENL HNFEQSAPAN GNLENQALRR SQPLKGPLHL TVPIISPTLL
GNSALLRPLR PKPPPLLPKP LITKELPPLA SIAQIISSVS SAPTLLKTDS IPTAPIGNST
GTEKSGNSKP NTTIMAAVQP DPGIPNDLPE RACSPNGSQK SPTPGSVKKR GRKKGTKNKP
KASSGVDLES SGEFASIEKM LATTDTNKFS TFLQSTADFK EVADRNGTSE EEREIAEDKP
LRGKRNAYSN CVQKIRCPHC PSVFPWASSL QRHMLTHTGQ KPHPCQKCDA FFSTKSNCER
HLLRRHGTAT YYLRRNGFVP QSKESDAGAH DSTDSQSDLD NTSGGSEALD LTSGEQDHPE
QATEFPEAST NSHKEEEKMD FSQGEDGKEE EERQEEAQEK SEGEEEPEED SVSNRSLDLN
FASKLMDFKL AESDQSTASG AQTEHKHTCD ICGKCFKFAG TLTRHKKAHA HDDGKDEKSN
EDGSKGFLGT AQVSIAQKDP ALEQEESGMD TKIVEATTDG EATGRENEES ESISEGESLE
RKSSEKSDDE RKPKANGGAK GESKADKRKK ICTVCNKRFW SLQDLTRHMR SHTGERPYKC
QTCERTFTLK HSLVRHQRIH QKIKSGKNHE KESDKEDVRS REEEEDSESE SLHSSTNPIS
ETECDLLVKQ ESSSPVTRSR KENLANAAKD PTSKEDRPAL RAAGPCPAES NKNTQKQAAK
EQESPRGKGD LESPSGFIQD LLEIHNKKPS MSHILASAES APQLLGVE
//
