ID H9H9Y8_NOMLE Unreviewed; 114 AA.
AC H9H9Y8;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Chemokine interleukin-8-like domain-containing protein {ECO:0000259|SMART:SM00199};
GN Name=LOC100580385 {ECO:0000313|Ensembl:ENSNLEP00000006984.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000006984.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000006984.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000006984.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the intercrine gamma family.
CC {ECO:0000256|ARBA:ARBA00006894}.
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DR RefSeq; XP_003282453.1; XM_003282405.2.
DR AlphaFoldDB; H9H9Y8; -.
DR STRING; 61853.ENSNLEP00000006984; -.
DR Ensembl; ENSNLET00000007331.2; ENSNLEP00000006984.1; ENSNLEG00000005765.2.
DR GeneID; 100580385; -.
DR KEGG; nle:100580385; -.
DR eggNOG; ENOG502S6ZP; Eukaryota.
DR GeneTree; ENSGT01100000263557; -.
DR HOGENOM; CLU_141716_2_0_1; -.
DR InParanoid; H9H9Y8; -.
DR OMA; IRSCCVV; -.
DR OrthoDB; 4639980at2759; -.
DR TreeFam; TF334888; -.
DR Proteomes; UP000001073; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0008009; F:chemokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00271; Chemokine_C; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR039809; Chemokine_b/g/d.
DR InterPro; IPR001811; Chemokine_IL8-like_dom.
DR InterPro; IPR008105; Chemokine_XCL1/XCL2.
DR InterPro; IPR036048; Interleukin_8-like_sf.
DR PANTHER; PTHR12015:SF101; CYTOKINE SCM-1 BETA-RELATED; 1.
DR PANTHER; PTHR12015; SMALL INDUCIBLE CYTOKINE A; 1.
DR Pfam; PF00048; IL8; 1.
DR PRINTS; PR01731; LYMPHOTACTIN.
DR SMART; SM00199; SCY; 1.
DR SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..114
FT /note="Chemokine interleukin-8-like domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003621808"
FT DOMAIN 28..84
FT /note="Chemokine interleukin-8-like"
FT /evidence="ECO:0000259|SMART:SM00199"
FT REGION 91..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 114 AA; 12561 MW; 5E652A707D177958 CRC64;
MRLLILALLG ICCLTAYIVE GVGTEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF
ITKRGLKVCA DPQARWVKDV VRSMDRKSNT RNNMIQTKPT GTQQSTTTAV TLTG
//
