ID H9UHA4_SPIAZ Unreviewed; 655 AA.
AC H9UHA4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN OrderedLocusNames=Spiaf_0803 {ECO:0000313|EMBL:AFG36897.1};
OS Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Spirochaetaceae;
OC Spirochaeta.
OX NCBI_TaxID=889378 {ECO:0000313|EMBL:AFG36897.1, ECO:0000313|Proteomes:UP000007383};
RN [1] {ECO:0000313|Proteomes:UP000007383}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 700263 / DSM 8902 / Z-7692
RC {ECO:0000313|Proteomes:UP000007383};
RX PubMed=23991249; DOI=10.4056/sigs.3607108;
RA Liolos K., Abt B., Scheuner C., Teshima H., Held B., Lapidus A., Nolan M.,
RA Lucas S., Deshpande S., Cheng J.F., Tapia R., Goodwin L.A., Pitluck S.,
RA Pagani I., Ivanova N., Mavromatis K., Mikhailova N., Huntemann M., Pati A.,
RA Chen A., Palaniappan K., Land M., Rohde M., Tindall B.J., Detter J.C.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Woyke T.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of the halophilic bacterium Spirochaeta africana
RT type strain (Z-7692(T)) from the alkaline Lake Magadi in the East African
RT Rift.";
RL Stand. Genomic Sci. 8:165-176(2013).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|RuleBase:RU362066}.
CC Periplasmic flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP003282; AFG36897.1; -; Genomic_DNA.
DR RefSeq; WP_014454894.1; NC_017098.1.
DR AlphaFoldDB; H9UHA4; -.
DR STRING; 889378.Spiaf_0803; -.
DR KEGG; sfc:Spiaf_0803; -.
DR PATRIC; fig|889378.3.peg.807; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_028399_0_0_12; -.
DR OrthoDB; 349896at2; -.
DR Proteomes; UP000007383; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:AFG36897.1};
KW Cilium {ECO:0000313|EMBL:AFG36897.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:AFG36897.1};
KW Periplasm {ECO:0000256|RuleBase:RU362066};
KW Reference proteome {ECO:0000313|Proteomes:UP000007383}.
FT DOMAIN 17..107
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 382..640
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT REGION 248..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 604..649
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 655 AA; 73131 MW; 9A2A45409B75CD99 CRC64;
MSDITIPGVN NRYFSQEQIQ DLVELEAAPI RRLERQIEEH EQVKRSWQDM SRNISALQGA
ARNLYGIDSP FRSRIAQSSN ESILTATASR HAEEERTDVV VKQTAATDRF ASDPLPGDYS
VPEGTYTFTV GDREHSLRFR GGNLDNFVTS INRRMGDAVR ARVVQDTPST RRLVIESRQE
GAENALGFDG DARQLALDLG IIEERLAVDR AIPLPDGRDE LAVGAEDSRQ IRVSPTAEEN
LRVSLEVRVT SRPEDSREVP ETPSGPRLPD SDSVTLRDVT VRDSGLAVDL PDMEPPEPPP
VVEDPDILFL RAGEREVRIP APPETGEYET IDISLRDYLE SGLDAIEIRN RNTLKDVSVR
NVRVYDPETR GDFAPRNALS TARDSIVNVD GIDFTRGSNR IEDIIPGTTL NIRRASTEPV
EVAVGPDRES VKDAIIEFVG YYNQLFTEAL ILSRGDEAIV DEIGYFTDEE REAAFERLGR
LRGDSTVNRI VRSLQSATSQ PFQTEREQHI SLLAQIGIST SSAQDGGGGI DPSRMRGYLQ
INENTLDEAL ANDFTAVRQL FGWDTDGDGA INSGAAFEVD RLMRPYVQTG GIIATRTSTI
DSSISRADRQ IETYSERLEN YEQRLRRDFA RMEGAIQQME SNAERFQNMN PGQQR
//
