ID H9UJS5_SPIAZ Unreviewed; 1073 AA.
AC H9UJS5;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Spiaf_1711 {ECO:0000313|EMBL:AFG37768.1};
OS Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Spirochaetaceae;
OC Spirochaeta.
OX NCBI_TaxID=889378 {ECO:0000313|EMBL:AFG37768.1, ECO:0000313|Proteomes:UP000007383};
RN [1] {ECO:0000313|Proteomes:UP000007383}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 700263 / DSM 8902 / Z-7692
RC {ECO:0000313|Proteomes:UP000007383};
RX PubMed=23991249; DOI=10.4056/sigs.3607108;
RA Liolos K., Abt B., Scheuner C., Teshima H., Held B., Lapidus A., Nolan M.,
RA Lucas S., Deshpande S., Cheng J.F., Tapia R., Goodwin L.A., Pitluck S.,
RA Pagani I., Ivanova N., Mavromatis K., Mikhailova N., Huntemann M., Pati A.,
RA Chen A., Palaniappan K., Land M., Rohde M., Tindall B.J., Detter J.C.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Woyke T.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of the halophilic bacterium Spirochaeta africana
RT type strain (Z-7692(T)) from the alkaline Lake Magadi in the East African
RT Rift.";
RL Stand. Genomic Sci. 8:165-176(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003282; AFG37768.1; -; Genomic_DNA.
DR AlphaFoldDB; H9UJS5; -.
DR STRING; 889378.Spiaf_1711; -.
DR KEGG; sfc:Spiaf_1711; -.
DR PATRIC; fig|889378.3.peg.1697; -.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG3292; Bacteria.
DR HOGENOM; CLU_000445_28_2_12; -.
DR OrthoDB; 9813394at2; -.
DR Proteomes; UP000007383; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07494; Reg_prop; 7.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 3.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AFG37768.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007383};
KW Transferase {ECO:0000313|EMBL:AFG37768.1}.
FT DOMAIN 851..1070
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1073 AA; 118786 MW; 063B193C21A31FAD CRC64;
MGSGLWRPVL AAVLLSIGGG NVTGDVGAAF DHLDYRDGLV NSSISAIVQD TDGFFWFGSQ
AGLHRYDGYS MEVISSLPFD PDSLSHHLVQ SLYYADDALW VGTYNGLNRL DLSDYRLQLF
PSREDDPYSL SNEIVTAVQR DAHGRYWVGT LDGLNRLDDP ESGRFTRIFA DPDDAQSLPH
STIRGILLDS RDRLWVGSYG GLSLLVSAPG SIPRFRSFDA ADGFSASYVM GIEEDDDGIL
WIGTWDKGVV RFDPEQEVFS YPDMPTYPVY SLHAAGEMLY AGTWGNGMLE YHIPTGQYRQ
YLHDPLVRRS IGHNVIYSLF LDDSGILWIG TNGNGISRLN THQSEFTLAH SQGDPDTALT
PSGVRALVQL PEGDLLVGFQ NHGIDRFREG EGVIRRYRSG TDNAQELPDG TVNDFLLRPD
GTVLTATNGG LLRYYPDQDR FEPVGYNPDP SGDVNENIIY SLAEDRQGSL WIGTYTRGIV
RRHPDGRLQR YETIPGQPDS LSNNLVYQIF VDSRGTVWAG TNGGLNRYLP SSDSWQRYQH
DPLDEGSISN DSVSSFLEDS AGQLWVGTRA GGINRYDPLS DSFVHWSTAD GLNSNAVMAI
AESLRGELLI GTSNGMSVFD PNEQEFFALA EADGMHAREF SGAVLSRDDG SVVFGAFGQL
VVVQDTVTPA SPNPPGTLIT DVQVQNRSII EGNPNRLEML EVSYRQNWLA FWFSSTDYTQ
PQNNRFRYRM QGWDEDWIEI EHRRSVEYTN LPPGRYQFQV QAGNSYGAWD TAVRRVDVVI
TPPFWQTTLF RAVLVLLILG LSLAINRYNT ARLRALNQRL DEQVKERTRE LSRINEELLE
ANAVKDRFFS VVAHDLRGPI FGIASYTAGL LDSDATLDFD EAIGSLATVR DTAVGLQQVL
EHLLEWGDLQ RSSEPVELQT VRVTDMLGTA VDSFRGLIET KQLSVDIESS DDLYASAAPH
LLSGIVQNLL HNAIKFTPVR GRIIMGAVRE RVPGMVSIDI IDNGIGMTAR QVEAIHQHKA
GSTVGTEGEK GSGLGLLLCM EQVKLLGGGL HIHSRVDQGT RVTITVPLDT HVP
//
