GenomeNet

Database: UniProt
Entry: HOX3_ORYSI
LinkDB: HOX3_ORYSI
Original site: HOX3_ORYSI 
ID   HOX3_ORYSI              Reviewed;         229 AA.
AC   Q9XH38; A2WT51; A5JPU0;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   18-SEP-2019, entry version 110.
DE   RecName: Full=Homeobox-leucine zipper protein HOX3;
DE   AltName: Full=HD-ZIP protein HOX3;
DE   AltName: Full=Homeodomain transcription factor HOX3;
DE   AltName: Full=OsHox3;
GN   Name=HOX3; ORFNames=OsI_002994;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBUNIT, AND TISSUE SPECIFICITY.
RC   STRAIN=cv. IR58; TISSUE=Seed embryo;
RX   PubMed=10732669; DOI=10.1007/pl00008671;
RA   Meijer A.H., de Kam R.J., d'Erfurth I., Shen W.-B., Hoge J.H.C.;
RT   "HD-Zip proteins of families I and II from rice: interactions and
RT   functional properties.";
RL   Mol. Gen. Genet. 263:12-21(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
RA   Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
RA   Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
RA   Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
RA   Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
RA   Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
RA   Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
RA   Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
RA   Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
RA   Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA   Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-101, TISSUE SPECIFICITY, GENE FAMILY,
RP   AND NOMENCLATURE.
RC   STRAIN=cv. Minghui 86;
RX   PubMed=17999151; DOI=10.1007/s11103-007-9255-7;
RA   Agalou A., Purwantomo S., Oevernaes E., Johannesson H., Zhu X.,
RA   Estiati A., de Kam R.J., Engstroem P., Slamet-Loedin I.H., Zhu Z.,
RA   Wang M., Xiong L., Meijer A.H., Ouwerkerk P.B.F.;
RT   "A genome-wide survey of HD-Zip genes in rice and analysis of drought-
RT   responsive family members.";
RL   Plant Mol. Biol. 66:87-103(2008).
CC   -!- FUNCTION: Probable transcription repressor that binds to the DNA
CC       sequence 5'-CAAT[GC]ATTG-3'. {ECO:0000269|PubMed:10732669}.
CC   -!- SUBUNIT: Homodimer (Probable). May form a heterodimer with HOX1,
CC       HOX2 or HOX7. {ECO:0000269|PubMed:10732669, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves, nodes,
CC       internodes, flowers and embryo. {ECO:0000269|PubMed:10732669,
CC       ECO:0000269|PubMed:17999151}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class II
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAY75147.1; Type=Erroneous initiation; Evidence={ECO:0000305};
DR   EMBL; AF145727; AAD37696.1; -; mRNA.
DR   EMBL; CM000126; EAY75147.1; ALT_INIT; Genomic_DNA.
DR   EMBL; EF555523; ABQ57266.1; -; mRNA.
DR   SMR; Q9XH38; -.
DR   eggNOG; KOG0483; Eukaryota.
DR   eggNOG; ENOG410Z2UE; LUCA.
DR   HOGENOM; HOG000241612; -.
DR   Proteomes; UP000007015; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR003106; Leu_zip_homeo.
DR   Pfam; PF02183; HALZ; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00340; HALZ; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    229       Homeobox-leucine zipper protein HOX3.
FT                                /FTId=PRO_0000331678.
FT   DNA_BIND     75    134       Homeobox. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00108}.
FT   REGION      133    177       Leucine-zipper.
FT   COMPBIAS     30     33       Poly-Asn.
FT   COMPBIAS     53     56       Poly-Glu.
SQ   SEQUENCE   229 AA;  25123 MW;  253D0A43DA9F1FC9 CRC64;
     MMGATSPSGL ELTMAVPGLS SSGSEGAGCN NNNAGGGCNM RDLDINQPAS GGEEEEFPMG
     SVEEDEEERG VGGPHRPKKL RLSKEQSRLL EESFRLNHTL TPKQKEALAI KLKLRPRQVE
     VWFQNRRART KLKQTEMECE YLKRCFGSLT EENRRLQREV EELRAMRVAP PTVLSPHTRQ
     PLPASALTMC PRCERITAAT GPPAVRPPPS SAAAAAPSPF HPRRPSAAF
//
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