ID I0AJX3_IGNAJ Unreviewed; 392 AA.
AC I0AJX3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=acetyl-CoA C-acetyltransferase {ECO:0000256|ARBA:ARBA00012705};
DE EC=2.3.1.9 {ECO:0000256|ARBA:ARBA00012705};
GN Name=atoB {ECO:0000313|EMBL:AFH49280.1};
GN OrderedLocusNames=IALB_1572 {ECO:0000313|EMBL:AFH49280.1};
OS Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 /
OS Mat9-16).
OC Bacteria; Ignavibacteriota; Ignavibacteria; Ignavibacteriales;
OC Ignavibacteriaceae; Ignavibacterium.
OX NCBI_TaxID=945713 {ECO:0000313|EMBL:AFH49280.1, ECO:0000313|Proteomes:UP000007394};
RN [1] {ECO:0000313|EMBL:AFH49280.1, ECO:0000313|Proteomes:UP000007394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16
RC {ECO:0000313|Proteomes:UP000007394};
RX PubMed=22661972; DOI=10.3389/fmicb.2012.00185;
RA Liu Z., Frigaard N.-U., Vogl K., Iino T., Ohkuma M., Overmann J.,
RA Bryant D.A.;
RT "Complete genome of Ignavibacterium album, a metabolically versatile,
RT flagellated, facultative anaerobe from the phylum Chlorobi.";
RL Front. Microbiol. 3:185-185(2012).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP003418; AFH49280.1; -; Genomic_DNA.
DR RefSeq; WP_014560433.1; NC_017464.1.
DR AlphaFoldDB; I0AJX3; -.
DR STRING; 945713.IALB_1572; -.
DR GeneID; 78243240; -.
DR KEGG; ial:IALB_1572; -.
DR PATRIC; fig|945713.3.peg.1573; -.
DR eggNOG; COG0183; Bacteria.
DR HOGENOM; CLU_031026_0_1_10; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000007394; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF171; ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000007394};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AFH49280.1}.
FT DOMAIN 4..261
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 268..389
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 347
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 377
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 41609 MW; 266787BAF5117BD9 CRC64;
MKKVVIVSAK RTPIGSFNGS LSSFTAGQLG SIAIKAVVED SKIDVNLIDE VIMGNVLMGG
QGQAPARQAA LFAGLPNKVE CMTINKMCGS GLKAVMIAQQ AILAGDADII IAGGQESMTN
TPYILPKARN GYRLGHGEVQ DLIVLDGLWD VYNQIHMGSC AEVCAKEFKF SREELDEFAI
NSYKRAINAT QTGRFKDEII PVKVAGKKGD TIVDKDEEPE RVIFEKIPSL KPVFEKDGVV
TAANASSIND GAAALLVMSE EKAKELGLKP LVELVAQASA AKAPIDFTTA PADAINKVLK
KANMSVNDID LYEINEAFAV VSLAVNKLLN LSVDKVNVNG GAVALGHPIG ASGARILTTL
IYEMKKRNVE YGLASLCIGG GEASALIVKN YQ
//
