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Database: UniProt
Entry: I0GMQ4_SELRL
LinkDB: I0GMQ4_SELRL
Original site: I0GMQ4_SELRL 
ID   I0GMQ4_SELRL            Unreviewed;       277 AA.
AC   I0GMQ4;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   11-DEC-2019, entry version 35.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254,
GN   ECO:0000313|EMBL:BAL82041.1};
GN   OrderedLocusNames=SELR_03330 {ECO:0000313|EMBL:BAL82041.1};
OS   Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421).
OC   Bacteria; Firmicutes; Negativicutes; Selenomonadales; Selenomonadaceae;
OC   Selenomonas.
OX   NCBI_TaxID=927704 {ECO:0000313|EMBL:BAL82041.1, ECO:0000313|Proteomes:UP000007887};
RN   [1] {ECO:0000313|EMBL:BAL82041.1, ECO:0000313|Proteomes:UP000007887}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 103574 / TAM6421 {ECO:0000313|Proteomes:UP000007887};
RA   Oguchi A., Ankai A., Kaneko J., Yamada-Narita S., Fukui S., Takahashi M.,
RA   Onodera T., Kojima S., Fushimi T., Abe N., Kamio Y., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome sequence of Selenomonas ruminantium subsp. lactilytica
RT   TAM6421.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934; EC=4.2.1.51;
CC         Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
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DR   EMBL; AP012292; BAL82041.1; -; Genomic_DNA.
DR   RefSeq; WP_014423486.1; NC_017068.1.
DR   STRING; 927704.SELR_03330; -.
DR   EnsemblBacteria; BAL82041; BAL82041; SELR_03330.
DR   GeneID; 31521620; -.
DR   KEGG; sri:SELR_03330; -.
DR   PATRIC; fig|927704.6.peg.344; -.
DR   KO; K04518; -.
DR   OMA; HTRFVIL; -.
DR   OrthoDB; 1280729at2; -.
DR   BioCyc; SRUM927704:G1H8D-359-MONOMER; -.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000007887; Chromosome.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Lyase {ECO:0000256|RuleBase:RU361254, ECO:0000313|EMBL:BAL82041.1};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254}.
FT   DOMAIN          4..183
FT                   /note="Prephenate dehydratase"
FT                   /evidence="ECO:0000259|PROSITE:PS51171"
FT   DOMAIN          196..277
FT                   /note="ACT"
FT                   /evidence="ECO:0000259|PROSITE:PS51671"
SQ   SEQUENCE   277 AA;  30637 MW;  C80B9496F0B0C97A CRC64;
     MAKTMGVLGP AGTHSEAAAV YLKKHCHEDY KLVLFADIFD CLQAVENGEV DSALVPVENS
     LEGAINISLD TLARSDGLHV WRELIWPVHN QLLAKRKGEI KRIYSHAQPI SQCRAFLQAH
     YPQAELIKVS STARAAEIVA DSEDDNCAAI ATARAGELLG LIPIAKEIQD SAANCTRFFQ
     VGREVLEFLP KEKLLVICQI DGQQAGALFD VLKEFAQRGI NMTRIESRPA RTELGAYIFF
     FDLEYVDSPQ LDESLAAVAE KSIWLRNLGT YPVIQVK
//
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