ID   I0GP76_SELRL            Unreviewed;      1194 AA.
AC   I0GP76;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   Name=addB {ECO:0000313|EMBL:BAL82563.1};
GN   OrderedLocusNames=SELR_08550 {ECO:0000313|EMBL:BAL82563.1};
OS   Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421).
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC   Selenomonas.
OX   NCBI_TaxID=927704 {ECO:0000313|EMBL:BAL82563.1, ECO:0000313|Proteomes:UP000007887};
RN   [1] {ECO:0000313|EMBL:BAL82563.1, ECO:0000313|Proteomes:UP000007887}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 103574 / TAM6421 {ECO:0000313|Proteomes:UP000007887};
RA   Oguchi A., Ankai A., Kaneko J., Yamada-Narita S., Fukui S., Takahashi M.,
RA   Onodera T., Kojima S., Fushimi T., Abe N., Kamio Y., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome sequence of Selenomonas ruminantium subsp. lactilytica
RT   TAM6421.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP012292; BAL82563.1; -; Genomic_DNA.
DR   RefSeq; WP_014424002.1; NC_017068.1.
DR   AlphaFoldDB; I0GP76; -.
DR   KEGG; sri:SELR_08550; -.
DR   PATRIC; fig|927704.6.peg.878; -.
DR   eggNOG; COG3857; Bacteria.
DR   HOGENOM; CLU_007838_0_0_9; -.
DR   OrthoDB; 9758506at2; -.
DR   Proteomes; UP000007887; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 6.10.140.1030; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR049035; ADDB_N.
DR   InterPro; IPR014140; DNA_helicase_suAddB.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   NCBIfam; TIGR02773; addB_Gpos; 1.
DR   PANTHER; PTHR30591; RECBCD ENZYME SUBUNIT RECC; 1.
DR   PANTHER; PTHR30591:SF1; RECBCD ENZYME SUBUNIT RECC; 1.
DR   Pfam; PF21445; ADDB_N; 1.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Helicase {ECO:0000313|EMBL:BAL82563.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:BAL82563.1};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          285..595
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
SQ   SEQUENCE   1194 AA;  136062 MW;  161D7B42CE6913A8 CRC64;
     MTATLDFIIG RSGTGKTHAC LTAMQKKMTA EPLGPALILL LPEHMTYKAE RELATMMEKN
     GQGFFRAYVF GFRRFARQIL LETGGGDMPR ISDVGRRLLL QKLLLKHQKD KDLTVFARAA
     RQRGFTETLS DAIKEIKSYR LTTDTLRQAA DMVGTGQERL SGKVRELSTL ADEFAAAMDG
     RTNDAEDLMN ILADKIPQAE LMQGAEVWID GFVFFNPQEM NVLAAILSSA AKVHITLPLT
     GEHLPNGQVN FQQPENTNET GLFNRPYRTM ENICRLLQEM ESGQSGFWQP VTLLTENHRA
     KNPALGWLEK TLFGQVAEYS EKVQGLRLVE AANRRIELET VAADILRLVR EEDYRYREIG
     VLIRNAEDYD GVLPLVFQDY GIPFFQDGKR QSIHHPLAEL LRSALEVVQR GWNYENIFRC
     LRTGFFPLVR DDVDKLENYV LEFGIRGRKR WLQAEDWRWH RRYSLDTEEE EVDAETQERL
     QLIDGLRRQA VEALRIFDQS IRQAENVTDQ ITALYDFLVA LEVPAHLVKW QEVAENEGRM
     ADAAEHKQIW EDIMELFDQL VEISGQEKMS LTDFAAVLGD GLDAVNLSLI PPGLDYVTVS
     SLDQNSMAGS RAIYILGANA GAMPRRIGEA GMFTDADRLH LADALEKMPA EFGEKPVISR
     GSQERSFGER FLLYRGFNEA SEYLWISYAL ADAEGSGLQP ASLVGKLKHC FPQLLFWSIP
     LEILDRKDML QLSAPVPAVS GLANALRGQR DEGKMDEFWQ DVYNWALKQP DLQRPMKLAL
     AGLAPKAPVG EIPTELAQAI YLKGKFLRGS VTQFEKFRQC PFSHFAKYGL KLQERHTYEF
     RHMDLGQLLH EVIREYGEMV SRDYDHRWQD VPEERRGDIC HELVETIAPR LQSEILLSRP
     DYRHYKRRME ATALQAVNHL SAWAAVSEFQ PAYFEEGFGH KADKVQLTPL PLGNGFSLSL
     KGQIDRLDIH QENPYFLILD YKTGQAAINL FEVYYGLKLQ LLVYVLVGQE LLKQQDKERL
     PAGILYALLH NPLITADKRL SSEEMAAAIK KKLTMPGWVL ADMDVIRSID ANLEHIKPQA
     KKDGQLDSNT LKKHYIRTQQ EFELMLGYVD YILRDTGKAI LSGDIQIKPY RNGERTACKY
     CDYQVLCGFD PDIEGFAYHD VQDFDEEEME RRMADTIGRE DLADAIHQGS TDSH
//