ID I0H4Z4_ACTM4 Unreviewed; 378 AA.
AC I0H4Z4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Putative alkane-1-monooxygenase {ECO:0000313|EMBL:BAL88081.1};
GN OrderedLocusNames=AMIS_28610 {ECO:0000313|EMBL:BAL88081.1};
OS Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 /
OS JCM 3121 / NBRC 102363 / NCIMB 12654 / NRRL B-3342 / UNCC 431).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=512565 {ECO:0000313|EMBL:BAL88081.1, ECO:0000313|Proteomes:UP000007882};
RN [1] {ECO:0000313|EMBL:BAL88081.1, ECO:0000313|Proteomes:UP000007882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NBRC 102363 /
RC NCIMB 12654 / NRRL B-3342 / UNCC 431
RC {ECO:0000313|Proteomes:UP000007882};
RA Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H.,
RA Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.;
RT "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC
RT 102363).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family. AlkB
CC subfamily. {ECO:0000256|ARBA:ARBA00010823}.
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DR EMBL; AP012319; BAL88081.1; -; Genomic_DNA.
DR RefSeq; WP_014442976.1; NC_017093.1.
DR AlphaFoldDB; I0H4Z4; -.
DR STRING; 512565.AMIS_28610; -.
DR KEGG; ams:AMIS_28610; -.
DR PATRIC; fig|512565.3.peg.2864; -.
DR eggNOG; COG3239; Bacteria.
DR HOGENOM; CLU_044462_1_0_11; -.
DR OrthoDB; 4759734at2; -.
DR Proteomes; UP000007882; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03512; Alkane-hydroxylase; 1.
DR InterPro; IPR033885; AlkB/XylM.
DR InterPro; IPR005804; FA_desaturase_dom.
DR PANTHER; PTHR38674; ALKANE 1-MONOOXYGENASE 1; 1.
DR PANTHER; PTHR38674:SF1; ALKANE 1-MONOOXYGENASE 1; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004}; Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:BAL88081.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000313|EMBL:BAL88081.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007882};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..334
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 378 AA; 42314 MW; 9C5D3C93B5B15EEC CRC64;
MTAALAWRDT KRPLWPLALV VPTLPFAALA ITLATGSAWG WWLTPVFILG VIPLIDVLVG
DDRDNPPDTA VPALLASRYY RWITYVFVPV QYAALVMACA VWSHGIGALG AAGLVLTAGL
VNGIAINTAH ELGHKRESVE RWLSKIALAP TGYGHFFVEH NRGHHVRVAT PEDPASARLG
ESYWRFWPRT VAGGLRSAWN LETNRHRLRQ RSPWSRHNDV LNAWAMTVAL FTVLCVAFGP
GVLAFLILQG IVGFSVLEAV NYLEHYGLLR QRNAAGRYEK VDPRHSWNSD RLTTNVFLFQ
LQRHSDHHAN PLRRYQTLRT FDVSPQLPAG YATMLLLALI PPLWRRVMDH RVLRHYGGEA
GRANAVAGYR PAREHHPA
//
