ID   I0HCT6_ACTM4            Unreviewed;       857 AA.
AC   I0HCT6;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Peptidase C14 caspase domain-containing protein {ECO:0000259|Pfam:PF00656};
GN   OrderedLocusNames=AMIS_56030 {ECO:0000313|EMBL:BAL90823.1};
OS   Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 /
OS   JCM 3121 / NBRC 102363 / NCIMB 12654 / NRRL B-3342 / UNCC 431).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=512565 {ECO:0000313|EMBL:BAL90823.1, ECO:0000313|Proteomes:UP000007882};
RN   [1] {ECO:0000313|EMBL:BAL90823.1, ECO:0000313|Proteomes:UP000007882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NBRC 102363 /
RC   NCIMB 12654 / NRRL B-3342 / UNCC 431
RC   {ECO:0000313|Proteomes:UP000007882};
RA   Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H.,
RA   Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.;
RT   "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC
RT   102363).";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AP012319; BAL90823.1; -; Genomic_DNA.
DR   RefSeq; WP_014445711.1; NC_017093.1.
DR   AlphaFoldDB; I0HCT6; -.
DR   STRING; 512565.AMIS_56030; -.
DR   KEGG; ams:AMIS_56030; -.
DR   PATRIC; fig|512565.3.peg.5600; -.
DR   eggNOG; COG4249; Bacteria.
DR   HOGENOM; CLU_333355_0_0_11; -.
DR   OrthoDB; 4464809at2; -.
DR   Proteomes; UP000007882; Chromosome.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   SUPFAM; SSF52129; Caspase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007882}.
FT   DOMAIN          17..224
FT                   /note="Peptidase C14 caspase"
FT                   /evidence="ECO:0000259|Pfam:PF00656"
FT   REGION          256..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          474..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   857 AA;  92936 MW;  06839CE48846CE08 CRC64;
     MARPHQPATW LPDPHRSRAV LVGVSAYDHL EALPAVERNL SALSELLTAP NLWGLRTQHC
     VTLHNPQSDE DVLDAVNTAA DQATDALIVY FAGHGLLDHR DELHLALSLA SRKRLYRTIR
     YDDLRREVVE TARNCRSKVV ILDCCYSGRA MQGAMGVLDV AEQTRIAGTY LMTATAETSK
     ALAPPGADYT AFTGALIDKI SAGILDGPEL LDLETLFYHL RADLLARRLP VPQQRSRNDG
     SAIALVRNLA YREAGGDAGD TIASHPPAPA PTPPPALPAQ MRQAAELTPL ATLARLRALR
     GSGDSRQADE LLAVAATHRR NQEVAALGAL LLREGLIEDF RTFAQYVARR STSNLLELLR
     TLDIIDAPDV ARGFMEAFAG GPPAETARLA KELRYEGLGK HLESLVDAAL RNSPDVASRT
     TLVGELWMAG LRDEVDYFVQ QVAPALSSGD VLALADELRT AGREDASSRL YAMAEPSGAG
     PSGPVADMAS PADSAAALDR SAERMTDEEI AELARSLRDA NHEDAALHLL STAVGVRPAA
     STLRLIDALR EVGRPVDAVE LLKVAAVTMP PKELAQLLSI LHDRGRRAEW STVLSSAGQR
     RQGDAAAVLQ ALGELGAVLT PAQIGTLTGE PDEAGLRAII ADLKPPWDFG ALAALLQYLI
     HRLGADGLGR FLLDLPRPDI RKLYFQAARA GNPTLSMVIR ALSPLDSIHW LFVIDATWQL
     GELVANLRKA GFDGHADAVL TEVSFSRTLP EILAIALQDL RHRGQDRDAD FLLSEIVDKR
     KFYAFRHGRS AYALLEVVFA LLAGGQDDEV RRAINRIPQT RHRAEILEFS ELLMKAGLAD
     LARRLLAAAD RRDRSPQ
//