ID I0HL76_RUBGI Unreviewed; 426 AA.
AC I0HL76;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=UDP-N-acetyl-D-mannosamine dehydrogenase WecC {ECO:0000313|EMBL:BAL93763.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:BAL93763.1};
GN Name=wecC {ECO:0000313|EMBL:BAL93763.1};
GN OrderedLocusNames=RGE_04180 {ECO:0000313|EMBL:BAL93763.1};
OS Rubrivivax gelatinosus (strain NBRC 100245 / IL144).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Rubrivivax.
OX NCBI_TaxID=983917 {ECO:0000313|EMBL:BAL93763.1, ECO:0000313|Proteomes:UP000007883};
RN [1] {ECO:0000313|EMBL:BAL93763.1, ECO:0000313|Proteomes:UP000007883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 100245 / IL144 {ECO:0000313|Proteomes:UP000007883};
RX PubMed=22689232; DOI=10.1128/JB.00511-12;
RA Nagashima S., Kamimura A., Shimizu T., Nakamura-isaki S., Aono E.,
RA Sakamoto K., Ichikawa N., Nakazawa H., Sekine M., Yamazaki S., Fujita N.,
RA Shimada K., Hanada S., Nagashima K.V.P.;
RT "Complete genome sequence of phototrophic betaproteobacterium Rubrivivax
RT gelatinosus IL144.";
RL J. Bacteriol. 194:3541-3542(2012).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; AP012320; BAL93763.1; -; Genomic_DNA.
DR RefSeq; WP_014426639.1; NC_017075.1.
DR AlphaFoldDB; I0HL76; -.
DR STRING; 983917.RGE_04180; -.
DR KEGG; rge:RGE_04180; -.
DR PATRIC; fig|983917.3.peg.411; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_1_4; -.
DR Proteomes; UP000007883; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:BAL93763.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007883}.
FT DOMAIN 313..413
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 426 AA; 46512 MW; 7AABCD51F5EBC6CF CRC64;
MNTVAVIGLG YVGLPLVVEF GKQMRTIGFD IAQHKVDACL AGTDPSRELP DSEMAAATHA
VYTSDPALLA EADVIIVAVP TPVDEAHIPD FKPLIGSSTS VGRHMKKGAI VVYESTVYPG
ATEEVCIPVL ERESGLKWKR DFFVGYSPER INPGDREHTL TKILKIVSGD TPETLEKVAQ
LYERIIVPGV HRASSIKTAE AAKVIENTQR DLNIALMNEL AIIFDKIGLD TSEVLEAAGT
KWNFLKFKPG LVGGHCIGVD PYYLTHKADM LGYHPQVILA GRRINDGMGK FIAEQTIKQM
IASGSYVKGA RVNVLGLTFK ENCGDLRNSK VIDIIHELES YGVDVFVTDA QAEPEEAMHE
YGVRLVPFEE LPRADAIVAA VAHREYAELS TDDLCRKLVK GGAFIDVKAA FDARALEAAG
CRVWRL
//
