ID I0I5Y5_CALAS Unreviewed; 1320 AA.
AC I0I5Y5;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Gingipain domain-containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CLDAP_26330 {ECO:0000313|EMBL:BAM00673.1};
OS Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 /
OS STL-6-O1).
OC Bacteria; Chloroflexota; Caldilineae; Caldilineales; Caldilineaceae;
OC Caldilinea.
OX NCBI_TaxID=926550 {ECO:0000313|EMBL:BAM00673.1, ECO:0000313|Proteomes:UP000007880};
RN [1] {ECO:0000313|EMBL:BAM00673.1, ECO:0000313|Proteomes:UP000007880}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1
RC {ECO:0000313|Proteomes:UP000007880};
RA Oguchi A., Hosoyama A., Sekine M., Fukai R., Kato Y., Nakamura S.,
RA Hanada S., Yamazaki S., Fujita N.;
RT "Complete genome sequence of Caldilinea aerophila DSM 14535 (= NBRC
RT 102666).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP012337; BAM00673.1; -; Genomic_DNA.
DR STRING; 926550.CLDAP_26330; -.
DR KEGG; cap:CLDAP_26330; -.
DR eggNOG; COG1572; Bacteria.
DR HOGENOM; CLU_259905_0_0_0; -.
DR Proteomes; UP000007880; Chromosome.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.380; -; 4.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR011635; CARDB.
DR InterPro; IPR001769; Gingipain.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR007280; Peptidase_C_arc/bac.
DR PANTHER; PTHR33794; BACILLOLYSIN; 1.
DR PANTHER; PTHR33794:SF1; BACILLOLYSIN; 1.
DR Pfam; PF07705; CARDB; 1.
DR Pfam; PF01364; Peptidase_C25; 1.
DR Pfam; PF04151; PPC; 2.
DR SUPFAM; SSF89260; Collagen-binding domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000007880};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 3..95
FT /note="CARDB"
FT /evidence="ECO:0000259|Pfam:PF07705"
FT DOMAIN 384..452
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT DOMAIN 516..585
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT DOMAIN 707..1019
FT /note="Gingipain"
FT /evidence="ECO:0000259|Pfam:PF01364"
FT REGION 602..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..631
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1320 AA; 141026 MW; F2D4EDF19D7A94A4 CRC64;
MPNPGETATV RMIFRNRGTA TSSPATFYFY VNPAERPPTQ ATAPSFFSGV PSLPPGGSSQ
FERSVTFASA GCDHIVYTWV DRDNLVADTD RSNNLVGLQV CVGVQCEVDA FESDDNADNA
GWLQVGVSQQ RSFCRTTPTG LSTLGDQDWV KFTAFRGLTY TLASLSPGIH ADPRITLWSG
GMQQVLAGPA GTLDWQPPAN GIYFAQVRNS NGKEGSGPLS GYTLSLSAVP AVTDAFEPDD
QCGQARTIST DGVRQTRLFQ APGDVDWVKF TIAAGETFAM VADNTGQGVN PLITLFSSCA
QSRSSDRVME GLNRVEDRSA SDQVYFARIA NQNPDRFGAD AHYSISVLAA ACIPDAQEED
DTRAQAKPLA LNTAQTHNVC PAGDQDWVKI ALTAGEIYVI RTANLGFAAD TVLELFDGQG
NRIAINDDYD YVRASRIVFE PSVSGNYYVM VRHHDPTAAG PNTNYDLIVE SGFCVPDEAD
AAGGDNGPGD ARQIATNGSA VARNFCADPL ARNLGDQDWF RFSAVAGARY HIHTEQLGPN
ADTVLSLYDR NGVTLLASND DSGAGLSAAI VFTPTVAGDY FVQARQYNTR VVGRESSYQL
RIEENLPPPP PPTPTPPPPT PTPTPPPPDP SEVRTLILVN RARLEAVHGP APASQIMDKL
FALADHPDVV GAVLQVESAP AVQGAYNAWL ASPTAFVDID LANAVSGAIR NTVLDFAASA
PNLAYLVIVG DDRIIPFHRV PEANLAKREN EYADALAGAD ALAAALAADM ILTDDFYADR
EPGTWKNGEL FVPDYAIGRL IQEPDEIIGQ IDVFLAGQTI DTQRALVTGY DFVQDSATQI
RNLLVNDGIP SISHADFIGP IWPGSLLRAL MLTSTPAGSR HDLVSINGHA THRSFGVPVG
GDIQASEVLT ATNNFTRTLV YNVGCHGGLN DPATLDLPQA FVRRGAVYVG NTGFGWGGSG
IVYSESLMRN FTRQLLTNTR ATVGPALMTA KQLYVSRARL IDGYDVKVLM QTTLYGLPMI
AITSGGTLSD DDPFPSVDDV ITPPGSFGEE TNVGSFRYGL PQSFGAFGAD DADPNYRVNL
DGNVDFAAGA PIQPGYYRDL TAPNAGALRG VLFLGGVYTE TSATAPIALA YNEYITDTTP
SAFDAPGWYP STPFAVQSSA FDDAVRDTVV LALGQYNPES GAQRVFDRMA FDTYYSDSPD
ITPPKILHVD AVLDAARGQG LFKVEASDAS GVTRVVIAHT DGAGVWSSKD LSYDAAALKW
TGTITATSTT RYFVQVVDGA GNIAIDDDKG RYYPLLPPLP LAPGRALEIR IFLPQVQRGN
//
