ID I0IPP5_LEPFC Unreviewed; 845 AA.
AC I0IPP5;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Putative DNA mismatch repair protein {ECO:0000313|EMBL:BAM07244.1};
GN Name=mutS {ECO:0000313|EMBL:BAM07244.1};
GN OrderedLocusNames=LFE_1562 {ECO:0000313|EMBL:BAM07244.1};
OS Leptospirillum ferrooxidans (strain C2-3).
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Leptospirillum.
OX NCBI_TaxID=1162668 {ECO:0000313|EMBL:BAM07244.1, ECO:0000313|Proteomes:UP000007382};
RN [1] {ECO:0000313|EMBL:BAM07244.1, ECO:0000313|Proteomes:UP000007382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C2-3 {ECO:0000313|EMBL:BAM07244.1,
RC ECO:0000313|Proteomes:UP000007382};
RX PubMed=22815442; DOI=10.1128/JB.00696-12;
RA Fujimura R., Sato Y., Nishizawa T., Oshima K., Kim S.-W., Hattori M.,
RA Kamijo T., Ohta H.;
RT "Complete Genome Sequence of Leptospirillum ferrooxidans Strain C2-3,
RT Isolated from a Fresh Volcanic Ash Deposit on the Island of Miyake,
RT Japan.";
RL J. Bacteriol. 194:4122-4123(2012).
RN [2] {ECO:0000313|Proteomes:UP000007382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C2-3 {ECO:0000313|Proteomes:UP000007382};
RA Fujimura R., Sato Y., Nishizawa T., Nanba K., Oshima K., Hattori M.,
RA Kamijo T., Ohta H.;
RT "The complete genome sequence of the pioneer microbe on fresh volcanic
RT deposit, Leptospirillum ferrooxidans strain C2-3.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP012342; BAM07244.1; -; Genomic_DNA.
DR AlphaFoldDB; I0IPP5; -.
DR STRING; 1162668.LFE_1562; -.
DR KEGG; lfc:LFE_1562; -.
DR PATRIC; fig|1162668.3.peg.1853; -.
DR eggNOG; COG0249; Bacteria.
DR HOGENOM; CLU_002472_1_3_0; -.
DR Proteomes; UP000007382; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007382}.
FT DOMAIN 697..713
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 845 AA; 94211 MW; D142E7C8AA5AF8FF CRC64;
MVKGIMDTEE MASQKRWVYP DTPLFRQYQG LREKAGEALL FFRLGDFYEL FGDQAVEVSR
VLGLTLTSRD RNKSNPLPMC GIPARSLELY LPRLVSLGYR IAISEQTQPD LESDGMFARE
IVRIVTRSTL IEDPSLEGGQ TKNGVCIVRM DESVAISSLD LSSGHLAVFE PQNKGDLDAI
LDWMASKSPV EILIADNELS VALSGIDHQR MSPSEIPLTE LLDVLPQGFE FPVLSPASER
ALSTLISYVA SLKAGIIHHL TGVTVEKTVG TLVIDRASIR HLDLVPDQED RKKNGSLLEV
LDQSRSSLGS RMLRRWVLAP LSDRETILLR QWIVKRMDEN PRWADRIGDI LGSTGDIERI
LGRIGMKGRL PRDLGGIRDG IQGAIELAKM PEWTELLPDH KRDASIEILS AMVLRLSGAL
VDDPPVSCGE SPVIRDGFDA ELDGYRHFER EGDQDLLKIE ERERRSTGID TLRIRYNQVA
GYYIEVTKGQ VSKVPSHYFR KQTLTGVERY TLPELMDFEQ RIAESRSRAQ QREFALLDEL
TTLVLSLSAQ IQRMAEFLGT VDALLSFARV GKKRQYVLPS FSMDGAMSIT NGRHPIVEAR
LMSGTFMPND TNLGSGTFVL LTGPNMAGKS TYMRQLALIQ IMAQMGAPVP ADSAVLPIVD
RILTRVGAND HILEGESTFM VEMKEVARVL RDATSKTLVI LDEVGRGTAT FDGMAIAWAV
SEYIHDHIRS MTLFATHYHE LHALTEKGQR FLNQSVAVRI EGGKIFFPHR ISSGHSSKSY
GIDVAKLAGV PEVVIERATR ILEHWNRQKP FKAISDGLSQ LPEKDSGALP LFNWKVRSDK
PTQSS
//
