ID I0IRH3_LEPFC Unreviewed; 1081 AA.
AC I0IRH3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:BAM07872.1};
GN OrderedLocusNames=LFE_2199 {ECO:0000313|EMBL:BAM07872.1};
OS Leptospirillum ferrooxidans (strain C2-3).
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Leptospirillum.
OX NCBI_TaxID=1162668 {ECO:0000313|EMBL:BAM07872.1, ECO:0000313|Proteomes:UP000007382};
RN [1] {ECO:0000313|EMBL:BAM07872.1, ECO:0000313|Proteomes:UP000007382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C2-3 {ECO:0000313|EMBL:BAM07872.1,
RC ECO:0000313|Proteomes:UP000007382};
RX PubMed=22815442; DOI=10.1128/JB.00696-12;
RA Fujimura R., Sato Y., Nishizawa T., Oshima K., Kim S.-W., Hattori M.,
RA Kamijo T., Ohta H.;
RT "Complete Genome Sequence of Leptospirillum ferrooxidans Strain C2-3,
RT Isolated from a Fresh Volcanic Ash Deposit on the Island of Miyake,
RT Japan.";
RL J. Bacteriol. 194:4122-4123(2012).
RN [2] {ECO:0000313|Proteomes:UP000007382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C2-3 {ECO:0000313|Proteomes:UP000007382};
RA Fujimura R., Sato Y., Nishizawa T., Nanba K., Oshima K., Hattori M.,
RA Kamijo T., Ohta H.;
RT "The complete genome sequence of the pioneer microbe on fresh volcanic
RT deposit, Leptospirillum ferrooxidans strain C2-3.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP012342; BAM07872.1; -; Genomic_DNA.
DR RefSeq; WP_014450355.1; NC_017094.1.
DR AlphaFoldDB; I0IRH3; -.
DR STRING; 1162668.LFE_2199; -.
DR GeneID; 78149873; -.
DR KEGG; lfc:LFE_2199; -.
DR PATRIC; fig|1162668.3.peg.2602; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_0; -.
DR OrthoDB; 9757876at2; -.
DR Proteomes; UP000007382; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF8; CATION EFFLUX PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007382};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 531..548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 904..926
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 932..952
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1008..1028
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1040..1062
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1081 AA; 119090 MW; 022C27018178C264 CRC64;
MFLVKGSLKS PYTIVAVALA FVLLGFESIS SMNVSIFPRI PTPQVEVLTL LPGLEVHNVE
MDLTEQLERF ILQAPYIRSI KSESMIGISL INVRFNSSYS TNAAVSMVVS MVYSALKYLP
PGTFPPVIIP FGVSAIPIGD IVLKSEKLNQ SQIYDIGYYN IRSQMGVVKG AAAPPVFGGL
SRQIQVYPEK EALLARGLSI WDVVKTLNSQ NVIWPAGFAK IGDSSYDVVV NALLGPMKDI
NNLPVTVKDG KPVFIKDIGV AKDSYRIQTN PVRIDGRKSV YIPLLKQEGA NTVKVVNATR
AALKTFYGLP KSLQLSLIFD QSVYIRESLA SLEREGAVGI ILTAFMILIF LGNFRATLII
ATSIPLSLLA GLIMLNATGQ TINIMTLGGL ALAIGRLVDD SIVVLENTNR HLEMGKAPYD
AALAGASEVA MPVLASTIAT MIVFSPVLFL QGKGRFLFTP LAAAVVFSMI ASYLVSMTLV
PVLSAWFLKS EADSGPKDTA FDRAFARFNQ VFDRFKNGYR HFLMEALSKK GLFSLLVALA
FISSLFLVSQ IKSGYFPSDD TGAFVIQMRL PVGSRIEMVD AYSTRVDAAI RRIIPKKDVV
HIVVNEGVRP GWASMYTNNL WSYMATILVQ LNPSDKRKHS MWYWESKIRP YLAEQFPNVG
FYFESSSIIT QILAGSGEAP IDIQVLGPSY RELGHLSKMI RDHIRKIPGT FNIRVKQNFH
YPVFQVNVDR NKAAFLGVSE LDVDKNVITS LATNNAIAED FWVDTRTGNP YFLTGQYPED
KINNLDDIKD IFIRRLEPIP FDAGGRSQLA FHRPQGWAGD KQDGGRPPIY LQDVAEFKRS
VNPTAVFHYD VERVVDVLVN FKHGDVYSLG EVGGKVEDYM KTVKLPEGYT WRETGMLASM
HRSFGSMGVA VLLAMALVYL ALVAQFQSFL DPFIIMVSVP FGLMGVLFML YATHSGINIE
SLIGIIMDIG IGVSNSVLLV EFAIRLREQG APLVRAVVEA GSVRLRPILM TAVGTVLAMI
PTAVGMGVGS GPEEPLARAV IGGLLVMTIL TLFQVPVLYV LIHQLEDRWE ERSKRRKAQK
A
//
