ID I0JNX2_HALH3 Unreviewed; 376 AA.
AC I0JNX2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Ribonucleotide-diphosphate reductase alpha subunit C-terminal domain {ECO:0000313|EMBL:CCG45842.1};
DE EC=1.17.4.1 {ECO:0000313|EMBL:CCG45842.1};
GN OrderedLocusNames=HBHAL_3498 {ECO:0000313|EMBL:CCG45842.1};
OS Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / KCTC
OS 3685 / LMG 17431 / NBRC 102448 / NCIMB 2269) (Sporosarcina halophila).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=866895 {ECO:0000313|EMBL:CCG45842.1, ECO:0000313|Proteomes:UP000007397};
RN [1] {ECO:0000313|EMBL:CCG45842.1, ECO:0000313|Proteomes:UP000007397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35676 / DSM 2266 / JCM 20832 / KCTC 3685 / LMG 17431 /
RC NBRC 102448 / NCIMB 2269 {ECO:0000313|Proteomes:UP000007397};
RX PubMed=22583374; DOI=10.1111/j.1462-2920.2012.02770.x;
RA Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V.,
RA Oesterhelt D.;
RT "Chloride and organic osmolytes: a hybrid strategy to cope with elevated
RT salinities by the moderately halophilic, chloride-dependent bacterium
RT Halobacillus halophilus.";
RL Environ. Microbiol. 15:1619-1633(2013).
CC -!- COFACTOR:
CC Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC Evidence={ECO:0000256|ARBA:ARBA00001922};
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DR EMBL; HE717023; CCG45842.1; -; Genomic_DNA.
DR AlphaFoldDB; I0JNX2; -.
DR STRING; 866895.HBHAL_3498; -.
DR KEGG; hhd:HBHAL_3498; -.
DR PATRIC; fig|866895.3.peg.2515; -.
DR eggNOG; COG0209; Bacteria.
DR HOGENOM; CLU_789055_0_0_9; -.
DR Proteomes; UP000007397; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:UniProtKB-EC.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR000788; RNR_lg_C.
DR PANTHER; PTHR43371:SF1; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR43371; VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE; 1.
DR Pfam; PF02867; Ribonuc_red_lgC; 1.
DR PRINTS; PR01183; RIBORDTASEM1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
PE 4: Predicted;
KW Cobalamin {ECO:0000256|ARBA:ARBA00022628};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CCG45842.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007397}.
FT DOMAIN 8..288
FT /note="Ribonucleotide reductase large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02867"
SQ SEQUENCE 376 AA; 41865 MW; F6BC7F95D45E5A48 CRC64;
MEQPLAPFSV CNLAAVNLAS VADKTEKKVN YEQLKQTVQT GVRMQDNVID ATPYFLEENK
VQALGERRVG LGVMGLHDLL IYCETEYGSE EGNKLVDEIF GVIATTAYRT SIELAKEKGS
FPFLQGTSEE ETNKLREAFI NTGYMKDMPE DIREGVMKYG IRNSHLLTVA PTGSTGTMVG
VSTGLEPYFS FSYYRSGRLG KFIEVKADIV NEYLEQHPDQ DPDHLPEWFV TAMTMSPEAH
ADTQCIIQRW VDSSISKTVN APRGYSVDQV EKVYQRLYRG GAKGGTVYVD GSRDSQVLTL
KAEENEFDGE QTEFEFEEER KPRVVLMDTV HELDKTNVTI GSEVGDTCPV CRKGTVEDIG
GCNTCTNCNA QLKCGL
//
