ID I0JPE6_HALH3 Unreviewed; 577 AA.
AC I0JPE6;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Diguanylate cyclase domain protein {ECO:0000313|EMBL:CCG46016.1};
GN OrderedLocusNames=HBHAL_3671 {ECO:0000313|EMBL:CCG46016.1};
OS Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / KCTC
OS 3685 / LMG 17431 / NBRC 102448 / NCIMB 2269) (Sporosarcina halophila).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=866895 {ECO:0000313|EMBL:CCG46016.1, ECO:0000313|Proteomes:UP000007397};
RN [1] {ECO:0000313|EMBL:CCG46016.1, ECO:0000313|Proteomes:UP000007397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35676 / DSM 2266 / JCM 20832 / KCTC 3685 / LMG 17431 /
RC NBRC 102448 / NCIMB 2269 {ECO:0000313|Proteomes:UP000007397};
RX PubMed=22583374; DOI=10.1111/j.1462-2920.2012.02770.x;
RA Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V.,
RA Oesterhelt D.;
RT "Chloride and organic osmolytes: a hybrid strategy to cope with elevated
RT salinities by the moderately halophilic, chloride-dependent bacterium
RT Halobacillus halophilus.";
RL Environ. Microbiol. 15:1619-1633(2013).
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DR EMBL; HE717023; CCG46016.1; -; Genomic_DNA.
DR RefSeq; WP_014643905.1; NC_017668.1.
DR AlphaFoldDB; I0JPE6; -.
DR STRING; 866895.HBHAL_3671; -.
DR KEGG; hhd:HBHAL_3671; -.
DR PATRIC; fig|866895.3.peg.2697; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR HOGENOM; CLU_032209_0_0_9; -.
DR Proteomes; UP000007397; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007397};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 429..571
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 577 AA; 66124 MW; 75EB572BC80B6463 CRC64;
MERDKRIKIW VLWACLWPSS IYLLYRSLDP PLQVNIWEIG AFVILASIVA LFPLRIGDNP
VFFTHGIAFA AFLQYGLFVE IIISQVSLLF LLLKVRVDRT SSHRIPINFL MFLAISVLSA
QVYYALGGEH AGEAVSSITD AIPIITYALS QIVLNQLSLK IITKIIYKQK IVWWDSGFVW
DIATAGIVLP VGFVLYIVFL EFGISAMFFV GIPFIFISGM LMLFHNSNEI NSYLKRTSKI
GHELTGKLGV KDVLDLFVDR LSELLPLDYI YVYDVLSENQ LKLIRFFDRS GVMNFSEVQM
NRGEGVSRAT WKKSGSFHYK KRAEWKHMTN SSTPENAESV LSVPVERNNE IVGIITIYSK
KKRAFVQFQF MILRILSNYL GVAIDNARHY EQRKEESERC PLTGLYNYRY FENYLQDLFL
QWETDDIKKP IALILLDIDH FKQVNDTYGH ESGNEILCLL SERLRMVLSN RGVLARYGGE
EFVILLPGYA AGQSINLAEE IKHAISSEPF YSHDHILRWE KVQEINVTAS IGVAVYPDDC
EEPLELIRHA DRAMYVGAKQ QGRNKVANYS QMNTNVQ
//
