ID I0JTW7_WHEAT Unreviewed; 343 AA.
AC I0JTW7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Protein-lysine N-methyltransferase CFC21_045341 {ECO:0000256|HAMAP-Rule:MF_03188};
DE EC=2.1.1.- {ECO:0000256|HAMAP-Rule:MF_03188};
GN ORFNames=CFC21_045341 {ECO:0000313|EMBL:KAF7034309.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EMBL:CCG48019.1};
RN [1] {ECO:0000313|EMBL:CCG48019.1}
RP NUCLEOTIDE SEQUENCE.
RA Bartos J., Vlcek C., Choulet F., Dzunkova M., Cvikova K., Safar J.,
RA Simkova H., Paces J., Strnad H., Sourdille P., Berges H., Cattonaro F.,
RA Feuillet C., Dolezel J.;
RT "Intraspecific sequence comparisons reveal similar rates of non-collinear
RT gene insertion in the B and D genomes of bread wheat.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF7034309.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7034309.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G020000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G020000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [4] {ECO:0000313|EnsemblPlants:TraesCS3D02G020000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7034309.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7034309.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: S-adenosyl-L-methionine-dependent protein-lysine N-
CC methyltransferase that methylates elongation factor 1-alpha.
CC {ECO:0000256|HAMAP-Rule:MF_03188}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03188}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. EFM4 family. {ECO:0000256|HAMAP-Rule:MF_03188}.
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DR EMBL; HE774676; CCG48019.1; -; Genomic_DNA.
DR EMBL; CM022219; KAF7034309.1; -; Genomic_DNA.
DR SMR; I0JTW7; -.
DR STRING; 4565.I0JTW7; -.
DR EnsemblPlants; TraesCS3D02G020000.1; TraesCS3D02G020000.1; TraesCS3D02G020000.
DR Gramene; TraesCAD_scaffold_071999_01G000200.1; TraesCAD_scaffold_071999_01G000200.1; TraesCAD_scaffold_071999_01G000200.
DR Gramene; TraesCLE_scaffold_088787_01G000400.1; TraesCLE_scaffold_088787_01G000400.1; TraesCLE_scaffold_088787_01G000400.
DR Gramene; TraesCS3D02G020000.1; TraesCS3D02G020000.1; TraesCS3D02G020000.
DR Gramene; TraesCS3D03G0035100.1; TraesCS3D03G0035100.1.CDS; TraesCS3D03G0035100.
DR Gramene; TraesPAR_scaffold_096803_01G000400.1; TraesPAR_scaffold_096803_01G000400.1; TraesPAR_scaffold_096803_01G000400.
DR Gramene; TraesRN3D0100039200.1; TraesRN3D0100039200.1; TraesRN3D0100039200.
DR Gramene; TraesROB_scaffold_088523_01G000400.1; TraesROB_scaffold_088523_01G000400.1; TraesROB_scaffold_088523_01G000400.
DR Gramene; TraesWEE_scaffold_104351_01G000200.1; TraesWEE_scaffold_104351_01G000200.1; TraesWEE_scaffold_104351_01G000200.
DR OMA; QERSHAD; -.
DR OrthoDB; 390334at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_03188; Methyltr_EFM4; 1.
DR InterPro; IPR026635; Efm4/METTL10.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12843; PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10; 1.
DR PANTHER; PTHR12843:SF6; PROTEIN-LYSINE N-METHYLTRANSFERASE OS01G0121100; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03188};
KW Methyltransferase {ECO:0000256|HAMAP-Rule:MF_03188,
KW ECO:0000313|EMBL:CCG48019.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_03188};
KW Transferase {ECO:0000256|HAMAP-Rule:MF_03188, ECO:0000313|EMBL:CCG48019.1}.
FT DOMAIN 172..299
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 343 AA; 36686 MW; 9C245EB0D9061DDE CRC64;
MAGIRWPPED PEMFPTRMLG TGVWGGPPAA AAGGGPPGEM ASDDDRSVAA DSWSIKSDYG
STLDDEQRYA DTAEVLLASC PSSASSSAAS AAAPSACSSS LSAHHSSDFS FDKDVPDVVP
PMLGLHNYQD GAYAEDLANY HERSHADDWF GTEAMDVLVG WTKNLCSSKD LPGCSVLDIG
TGSGRLLQQL AKQGFSDLTG IDYSEAAIEL ARNLAIRDGF EHINFLVDDV LESKLERRFE
LVMDEGTLDA IGLHPDGPVK RMMYWQSVAS LVSPGGILVI TSCSRTKDEL VQEVENFNQR
KLGAMVSEGA LASDAVVFKY LDHVQAYPNV DGVCIATVAF LHT
//
