ID I0JW13_METFB Unreviewed; 432 AA.
AC I0JW13;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Nuclease of restriction endonuclease-like fold,RmuC family {ECO:0000313|EMBL:CCG91432.1};
GN ORFNames=MFUM_1030015 {ECO:0000313|EMBL:CCG91432.1};
OS Methylacidiphilum fumariolicum (strain SolV).
OC Bacteria; Verrucomicrobiota; Methylacidiphilae; Methylacidiphilales;
OC Methylacidiphilaceae; Methylacidiphilum (ex Ratnadevi et al. 2023).
OX NCBI_TaxID=1156937 {ECO:0000313|EMBL:CCG91432.1, ECO:0000313|Proteomes:UP000004837};
RN [1] {ECO:0000313|EMBL:CCG91432.1, ECO:0000313|Proteomes:UP000004837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SolV {ECO:0000313|EMBL:CCG91432.1,
RC ECO:0000313|Proteomes:UP000004837};
RX PubMed=22740660; DOI=10.1128/JB.00501-12;
RA Khadem A.F., Wieczorek A.S., Pol A., Vuilleumier S., Harhangi H.R.,
RA Dunfield P.F., Kalyuzhnaya M.G., Murrell J.C., Francoijs K.-J.,
RA Stunnenberg H.G., Stein L.Y., DiSpirito A.A., Semrau J.D., Lajus A.,
RA Medigue C., Klotz M.G., Jetten M.S.M., Op den Camp H.J.M.;
RT "Draft Genome Sequence of the Volcano-Inhabiting Thermoacidophilic
RT Methanotroph Methylacidiphilum fumariolicum Strain SolV.";
RL J. Bacteriol. 194:3729-3730(2012).
CC -!- FUNCTION: Involved in DNA recombination.
CC {ECO:0000256|ARBA:ARBA00003416}.
CC -!- SIMILARITY: Belongs to the RmuC family.
CC {ECO:0000256|ARBA:ARBA00009840}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCG91432.1}.
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DR EMBL; CAHT01000006; CCG91432.1; -; Genomic_DNA.
DR RefSeq; WP_009058377.1; NZ_CAHT01000006.1.
DR AlphaFoldDB; I0JW13; -.
DR STRING; 1156937.GCA_000953475_01023; -.
DR eggNOG; COG1322; Bacteria.
DR InParanoid; I0JW13; -.
DR Proteomes; UP000004837; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR InterPro; IPR003798; DNA_recombination_RmuC.
DR PANTHER; PTHR30563; DNA RECOMBINATION PROTEIN RMUC; 1.
DR PANTHER; PTHR30563:SF0; DNA RECOMBINATION PROTEIN RMUC; 1.
DR Pfam; PF02646; RmuC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000313|EMBL:CCG91432.1};
KW Hydrolase {ECO:0000313|EMBL:CCG91432.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Nuclease {ECO:0000313|EMBL:CCG91432.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004837};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 28..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 132..159
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 432 AA; 49497 MW; 30004C9D5B52F3E5 CRC64;
MNSFFLVSFL VGVGIGFLLT LLLLRPRYIL LQKDLERYKN ENEDLINLQA QNKDLELQIA
TLEAQKKAQQ EQILWVTAAQ DTLKTMFQSL ALQVLESNSK NILEQATYQF HSLFESMKAD
WNLKKQEFKE IVMPIEKSLE ALDQQIKNLE SKREGAYSSL STHLTHLSEA YKELHESAIK
LEQSLKSPLV RGSWGEYQLQ RLVEMAGMKE HVSYIPQPPD ADKRADMIIY IPGNRKIYVD
AKTPMGAYLE AMTADNETTR KTKLKEHLAA VKERIRELGK KEYGQNQTDA FEYVIMFLPN
EGLLSVSFEA DPEIFQYALE RKVLLASPIN FLALLKAIAL GWQQQQMTEE VEKIAYEIKE
LYSSFVELME LLNRLRKALG SSMEAFNKIA TLCQGKIIPS TKKIKTSGAF SEEVSDVHEI
EPTLKDIPFQ QT
//
