ID I0JX58_METFB Unreviewed; 574 AA.
AC I0JX58;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MFUM_230006 {ECO:0000313|EMBL:CCG91827.1};
OS Methylacidiphilum fumariolicum (strain SolV).
OC Bacteria; Verrucomicrobiota; Methylacidiphilae; Methylacidiphilales;
OC Methylacidiphilaceae; Methylacidiphilum (ex Ratnadevi et al. 2023).
OX NCBI_TaxID=1156937 {ECO:0000313|EMBL:CCG91827.1, ECO:0000313|Proteomes:UP000004837};
RN [1] {ECO:0000313|EMBL:CCG91827.1, ECO:0000313|Proteomes:UP000004837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SolV {ECO:0000313|EMBL:CCG91827.1,
RC ECO:0000313|Proteomes:UP000004837};
RX PubMed=22740660; DOI=10.1128/JB.00501-12;
RA Khadem A.F., Wieczorek A.S., Pol A., Vuilleumier S., Harhangi H.R.,
RA Dunfield P.F., Kalyuzhnaya M.G., Murrell J.C., Francoijs K.-J.,
RA Stunnenberg H.G., Stein L.Y., DiSpirito A.A., Semrau J.D., Lajus A.,
RA Medigue C., Klotz M.G., Jetten M.S.M., Op den Camp H.J.M.;
RT "Draft Genome Sequence of the Volcano-Inhabiting Thermoacidophilic
RT Methanotroph Methylacidiphilum fumariolicum Strain SolV.";
RL J. Bacteriol. 194:3729-3730(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCG91827.1}.
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DR EMBL; CAHT01000026; CCG91827.1; -; Genomic_DNA.
DR RefSeq; WP_009059086.1; NZ_CAHT01000026.1.
DR AlphaFoldDB; I0JX58; -.
DR STRING; 1156937.GCA_000953475_00917; -.
DR eggNOG; COG1956; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR InParanoid; I0JX58; -.
DR Proteomes; UP000004837; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CCG91827.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000004837};
KW Transferase {ECO:0000313|EMBL:CCG91827.1}.
FT DOMAIN 363..574
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 574 AA; 64309 MW; 0119326A73C39CF9 CRC64;
MKSASEDKNN VFTAKKAGLL SINKIKRLLT VQGVIRHFLK IAIDITQSDS GSFVLFNPNT
GFLDIEASFG LKRRAKKTKL RVGEGITGWV ATSGKTLRID DVSKDWRYVS IDPRIRSELA
VPIEWQSTIV GVLNVDSHEK SHYKPQHEKQ LETIASEAAQ WLSYAWEIDK LRQQAKQLST
LIEIGRTIVS QEDLEKTLEG VVRNAVFFMD ANKGKLFLLN REKSELLLIA SYDSNKEDIK
KEKMVISLSE SIFGVVVKKC KPLAIQDIHE ESLMHCPEFA LENKMVSFLA VPLVFGKECQ
GLLAIFTSTP HRFSNSQIQL LQTLADLSAV ALAKARLLER IVQTEENLRE GERLLSLGLL
AAEIAHEIRN PLTVIHMLLH SLKMRIKEDP VSQRDLEVLE KKMSQLNRIV DQVLVIGRST
EPTLEAMKVE DIIDDVLLLS RHKLAGQRIE VQTKISPMLP NLKADRAQVE QAVLNLILNA
IQAMGEGGML EIIADIQHDD AEPYLAIRVK DTGSGMTQAE IEDIFVPFLT RKKEGTGLGL
AIVQKIMENH RGKVEVHSTL GQGSTFSLLF PLLD
//
