ID I0K248_9BACT Unreviewed; 800 AA.
AC I0K248;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Macrolide export ATP-binding/permease protein macB {ECO:0008006|Google:ProtNLM};
GN ORFNames=FAES_0187 {ECO:0000313|EMBL:CCG98201.1};
OS Fibrella aestuarina BUZ 2.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrella.
OX NCBI_TaxID=1166018 {ECO:0000313|EMBL:CCG98201.1, ECO:0000313|Proteomes:UP000011058};
RN [1] {ECO:0000313|EMBL:CCG98201.1, ECO:0000313|Proteomes:UP000011058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 2T {ECO:0000313|Proteomes:UP000011058};
RX PubMed=22689241; DOI=10.1128/JB.00550-12;
RA Filippini M., Qi W., Blom J., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of Fibrella aestuarina BUZ 2T, a Filamentous Marine
RT Bacterium.";
RL J. Bacteriol. 194:3555-3555(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC {ECO:0000256|ARBA:ARBA00038076}.
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DR EMBL; HE796683; CCG98201.1; -; Genomic_DNA.
DR RefSeq; WP_015329301.1; NC_020054.1.
DR AlphaFoldDB; I0K248; -.
DR STRING; 1166018.FAES_0187; -.
DR KEGG; fae:FAES_0187; -.
DR PATRIC; fig|1166018.3.peg.189; -.
DR eggNOG; COG0577; Bacteria.
DR HOGENOM; CLU_008713_1_0_10; -.
DR OrthoDB; 5933722at2; -.
DR Proteomes; UP000011058; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR025857; MacB_PCD.
DR PANTHER; PTHR30572:SF4; MACROLIDE EXPORT ATP-BINDING_PERMEASE PROTEIN MACB; 1.
DR PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR Pfam; PF02687; FtsX; 2.
DR Pfam; PF12704; MacB_PCD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011058};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..741
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 761..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..242
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 287..400
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
FT DOMAIN 429..620
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 680..786
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
SQ SEQUENCE 800 AA; 87608 MW; B42E369DFDBDA268 CRC64;
MLQNYITIAW RNLLRRKVYA ALNIVGLAVG LTFFCLIGSY VWGEYQVNQS LRNADRQCLI
QSRWKQENMG MDITSLAPIG PALRATYPQL VANYYRFHGV SATLSKGANH FRESMQIGDS
TLLTMYGFRL LQGNPRTALA APNAIVLTAT KAQKLFGRAD VLNQLVTIET PQGGKQELLV
TGVLDELPPN SVSNLLAEAN EVFLSPGSLA SFGADLTVWA NPYIVNYIEL QPGVTPQDLV
KPMAQLIATN APAELAQNLT AYVTPLTDYY LQSNNGLVHK MIVTLSLVAV FILLMAVVNF
VNLATGSSAV RLREIGVRKA LGGLRQQLTA QFLIEAMVLT GLAAVLAVGL YVALRPVFDQ
VVGKPLPALS ALPWRYGWLL PVLVLLVGAL AGSYPALYLS AYSSVDSLKG KSRSESVLFR
RGLVTLQFAI AVFVFVGAVV VSRQVTFFFN TDLGFKKEAV LTVSSLPRNW SPEGVARMEA
ARDRFARLPG IQAASLSYEI PNGNVGNSAN LFPEGRDSTQ AVSVKLMTTD EQYAQTYQIT
LKGGRYFHQG RAGSDSTSVV LNEASIKTLG YPTTEAALGQ AVRMQGDPRR YTIRGVVQNF
HVGTLHKAID PLAIVHLQSR PLYRFFSFRL ATGNPRPTID RMEQTWREQF PDAPFDYAFM
DQTLAKLYKT ELQMEKAAYV ATALALLIVL LGVAGLVSLS VARRTKEVGI RKVLGASVPG
IVVLFLNEYV WMLLLANLLA WPVAYWAVSG WLADYAYHTP IGWQPFVGVA LLLALITAIL
IGLQVVKTAL VNPIKSLRTE
//
