ID I0K636_9BACT Unreviewed; 426 AA.
AC I0K636;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=UDP-N-acetyl-D-galactosamine dehydrogenase {ECO:0000313|EMBL:CCG99589.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:CCG99589.1};
GN Name=wbgT {ECO:0000313|EMBL:CCG99589.1};
GN ORFNames=FAES_1579 {ECO:0000313|EMBL:CCG99589.1};
OS Fibrella aestuarina BUZ 2.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrella.
OX NCBI_TaxID=1166018 {ECO:0000313|EMBL:CCG99589.1, ECO:0000313|Proteomes:UP000011058};
RN [1] {ECO:0000313|EMBL:CCG99589.1, ECO:0000313|Proteomes:UP000011058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 2T {ECO:0000313|Proteomes:UP000011058};
RX PubMed=22689241; DOI=10.1128/JB.00550-12;
RA Filippini M., Qi W., Blom J., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of Fibrella aestuarina BUZ 2T, a Filamentous Marine
RT Bacterium.";
RL J. Bacteriol. 194:3555-3555(2012).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; HE796683; CCG99589.1; -; Genomic_DNA.
DR RefSeq; WP_015330688.1; NC_020054.1.
DR AlphaFoldDB; I0K636; -.
DR STRING; 1166018.FAES_1579; -.
DR KEGG; fae:FAES_1579; -.
DR PATRIC; fig|1166018.3.peg.3314; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_1_10; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000011058; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CCG99589.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011058}.
FT DOMAIN 321..419
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 426 AA; 46925 MW; 373E7A0495909DE6 CRC64;
MLSHLSSGQL QIGIIGLGYV GLPLAIEFGK EWPTIGFDIN QVRVDALRKG IDHTREVSEQ
AFGASQHVRF TGNMADLAAC TVYIVTVPTP IDKYKSPDLT ALLAASRMVG AHLKRGDLVV
YESTVYPGCT EEDCVPVLEA ASGLRYNDDF FCGYSPERIN PGDKERNVSQ ILKITSGSTP
AAARYVDQLY SRIIKAGTYP APSIKVAEAA KAIENAQRDV NISFVNELAL IFDRLGIDTM
DVLEAAATKW NFLKFRPGLV GGHCISVDPY YLAHKAQSVG YHPQVILSGR RVNDDMPIYV
ANKLVKAMIR AGLSIAGSSV LLLGATFKEN CPDIRNTKVV DIYQELTGFG MKVDIYDPWA
SADEVYAEYG IRLVEQPGRC RYDGVILTVA HDEFLTLDLQ ELCRSELSII YDLKSVLDRT
KVSMRI
//
