ID I0K7Z6_9BACT Unreviewed; 466 AA.
AC I0K7Z6;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:CCH00249.1};
DE EC=3.2.1.51 {ECO:0000313|EMBL:CCH00249.1};
GN ORFNames=FAES_2240 {ECO:0000313|EMBL:CCH00249.1};
OS Fibrella aestuarina BUZ 2.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrella.
OX NCBI_TaxID=1166018 {ECO:0000313|EMBL:CCH00249.1, ECO:0000313|Proteomes:UP000011058};
RN [1] {ECO:0000313|EMBL:CCH00249.1, ECO:0000313|Proteomes:UP000011058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 2T {ECO:0000313|Proteomes:UP000011058};
RX PubMed=22689241; DOI=10.1128/JB.00550-12;
RA Filippini M., Qi W., Blom J., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of Fibrella aestuarina BUZ 2T, a Filamentous Marine
RT Bacterium.";
RL J. Bacteriol. 194:3555-3555(2012).
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
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DR EMBL; HE796683; CCH00249.1; -; Genomic_DNA.
DR RefSeq; WP_015331348.1; NC_020054.1.
DR AlphaFoldDB; I0K7Z6; -.
DR STRING; 1166018.FAES_2240; -.
DR KEGG; fae:FAES_2240; -.
DR PATRIC; fig|1166018.3.peg.3996; -.
DR eggNOG; COG3669; Bacteria.
DR HOGENOM; CLU_002934_1_1_10; -.
DR OrthoDB; 107551at2; -.
DR Proteomes; UP000011058; Chromosome.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR031919; Fucosidase_C.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR Pfam; PF16757; Fucosidase_C; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:CCH00249.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CCH00249.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011058};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..466
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003630295"
FT DOMAIN 389..463
FT /note="Alpha-L-fucosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16757"
FT SITE 300
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 466 AA; 53224 MW; C675AA92C0370F9C CRC64;
MYRPLLTLLL ILCITCSTLA QQRYEANWAS IDSRPVPAWF EDAKFGIFIH WGLFSVPAFG
PTARDSVGVY DRYAEWYWRK STDSNPKNKT YPIFKRFEER TYGPNHKYQD FVEGFTCDFF
KPDDWADVFR QSGAKYVVLT SKHHEGFTLW PSAQAWNWNA ADVGPHRDLA GDLIKAVKAK
GIRMGYYYSL YEWFNPLYKT DVAGYVDRHM LPQMKDLVTR YQPDIVWTDG EWDHPSETWR
STEFLAWLYN ESPVKQDVVV NDRWGKETRG KHGGIFTTEY DLVHDANSEG MAFSRPWEEC
RGIGSSFGYN RAENLEDYST SKQLIDILVD KVARGGNLLL NIGPTADGRI PVIMQQRLKD
IGDWLTVNGE AIYGTRKWEK SPKVDSKTTL FFTKKGNDLY AICTRWPDAP LTIPGVRKPK
RVSLLGYAGN VPVKSSGNGL ALTAPTLSPG TIPCQHAWVF KLEGAL
//
