ID   I0L014_9ACTN            Unreviewed;       458 AA.
AC   I0L014;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:CCH17161.1};
DE            EC=3.1.3.1 {ECO:0000313|EMBL:CCH17161.1};
GN   ORFNames=MILUP08_42081 {ECO:0000313|EMBL:CCH17161.1};
OS   Micromonospora lupini str. Lupac 08.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH17161.1, ECO:0000313|Proteomes:UP000003448};
RN   [1] {ECO:0000313|Proteomes:UP000003448}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX   PubMed=22815450; DOI=10.1128/jb.00628-12;
RA   Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA   Carro L., Coll P., Trujillo M.E.;
RT   "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT   Nodules of Lupinus angustifolius.";
RL   J. Bacteriol. 194:4135-4135(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCH17161.1}.
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DR   EMBL; CAIE01000017; CCH17161.1; -; Genomic_DNA.
DR   RefSeq; WP_007457615.1; NZ_HF570108.1.
DR   AlphaFoldDB; I0L014; -.
DR   STRING; 1150864.MILUP08_42081; -.
DR   eggNOG; COG1409; Bacteria.
DR   OrthoDB; 9804511at2; -.
DR   Proteomes; UP000003448; Unassembled WGS sequence.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   NCBIfam; NF033679; DNRLRE_dom; 1.
DR   PANTHER; PTHR45867:SF3; ACID PHOSPHATASE TYPE 7; 1.
DR   PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:CCH17161.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003448};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..35
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           36..458
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003630908"
FT   DOMAIN          229..377
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   458 AA;  47654 MW;  3F2B819D2C41A1F6 CRC64;
     MDIRIARPPV TIGTVAVLVA ATAAVVLTGS GAASAASVTF TPVADTYVQS DTASTNYGTS
     TQVVVDNSPA RRMFLRFTVS GVSGTVSSAK LRLRTISGNS GSDAGGTFRT MSNTTWSETG
     TTWSNQPTID GATLGSLGTV AGNTWYEVDV TSAVTGNGTY SFGATSASGD GAYYDTRESG
     GDAPQLVVTT GTTTPPSGDP VLVGAGDIAT SGSGDTATAA LLDGISGTVF TTGDNVYDSG
     TASQFASYYE PTWGRHKART RPSPGNHDYN TSGATGYYNY FGTSAGPSGR GYYSFDLGNW
     HIVSLNSNVS TSAGSTQEQW LRADLAASSK PCTLAYWHHP LFTSSSNHAP STSTRPLYQA
     LYDYNADVVV WGHNHVYERF GPMNPAGGYD ASRGMRSFVA GMGGADHYGF GTIQPNSEAR
     NSSAFGVLKF TLHSGSYDWQ FVPVAGQTYN DSGTGACH
//